(Q27339381)

26 June 2017

title

Abasic pivot substitution harnesses target specificity of RNA interference (English)

1 reference

26 June 2017

1 reference

Hye-Sook Lee

1

Hye-Sook

Lee

1 reference

26 June 2017

Heeyoung Seok

2

Heeyoung

Seok

1 reference

26 June 2017

Dong Ha Lee

3

Dong Ha

Lee

1 reference

26 June 2017

Juyoung Ham

4

Juyoung

Ham

1 reference

26 June 2017

Wooje Lee

5

Wooje

Lee

1 reference

26 June 2017

Emilia Moonkyung Youm

6

Emilia Moonkyung

Youm

1 reference

26 June 2017

Jin Seon Yoo

7

Jin Seon

Yoo

1 reference

26 June 2017

Yong-Seung Lee

8

Yong-Seung

Lee

1 reference

26 June 2017

Eun-Sook Jang

9

Eun-Sook

Jang

1 reference

26 June 2017

Sung Wook Chi

10

Sung Wook

Chi

1 reference

26 June 2017

language of work or name

English

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publication date

18 December 2015

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26 June 2017

published in

Nature Communications

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26 June 2017

volume

6

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26 June 2017

page(s)

10154

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Creative Commons Attribution 4.0 International

26 June 2017

copyright license

start time

1 December 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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21 March 2017

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21 March 2017

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21 March 2017

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The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing

21 March 2017

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siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

21 March 2017

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CLIP identifies Nova-regulated RNA networks in the brain

21 March 2017

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Facile means for quantifying microRNA expression by real-time PCR

21 March 2017

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Purified Argonaute2 and an siRNA form recombinant human RISC

21 March 2017

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Mechanisms of gene silencing by double-stranded RNA

21 March 2017

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Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs

21 March 2017

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Expression profiling reveals off-target gene regulation by RNAi

21 March 2017

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siRNAs can function as miRNAs

7 April 2017

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Structural basis for microRNA targeting

7 April 2017

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Transcriptome-wide discovery of microRNA binding sites in human brain.

29 September 2017

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RNA duplexes with abasic substitutions are potent and allele-selective inhibitors of huntingtin and ataxin-3 expression

29 September 2017

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miRTCat: a comprehensive map of human and mouse microRNA target sites including non-canonical nucleation bulges

29 September 2017

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Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding

29 September 2017

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An alternative mode of microRNA target recognition

29 September 2017

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A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

29 September 2017

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Modified siRNA structure with a single nucleotide bulge overcomes conventional siRNA-mediated off-target silencing.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Digital transcriptome profiling using selective hexamer priming for cDNA synthesis

29 September 2017

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MicroRNA-like off-target transcript regulation by siRNAs is species specific.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation

29 September 2017

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Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Enhancing and confirming the specificity of RNAi experiments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

On the art of identifying effective and specific siRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Off-target effects by siRNA can induce toxic phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Unlocking the potential of the human genome with RNA interference

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Gene silencing in mammals by small interfering RNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4703836

Minimizing the risk of reporting false positives in large-scale RNAi screens

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10154

A 'pivotal' new rule for microRNA-mRNA interactions.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10154

21 January 2018

Identifiers

DOI

10.1038/NCOMMS10154

1 reference

Dimensions Publication ID

26 June 2017

0 references

1000733895

0 references

OpenCitations bibliographic resource ID

2059207

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2059207

1 reference