(Q27638321)

2

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Daniel Lim

3

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John S Elce

4

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Zongchao Jia

5

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Peter L Davies

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

6

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language of work or name

English

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publication date

8 March 2002

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published in

Cell

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volume

108

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issue

5

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page(s)

649-60

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Structure of calmodulin refined at 2.2 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

The death substrate Gas2 binds m-calpain and increases susceptibility to p53-dependent apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Alignment/phylogeny of the papain superfamily of cysteine proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Expression, partial purification and functional properties of themuscle-specific calpain isoform p94.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calpain: a protease in search of a function?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

v-Src-induced modulation of the calpain-calpastatin proteolytic system regulates transformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Regulation of integrin-mediated adhesion during cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Studies of the active site of m-calpain and the interaction with calpastatin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calcium-activated neutral protease (calpain) system: structure, function, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Roles of individual EF-hands in the activation of m-calpain by calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Recombinant calpain II: improved expression systems and production of a C105A active-site mutant for crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Cutting to the chase: calpain proteases in cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calpain mutants with increased Ca2+ sensitivity and implications for the role of the C(2)-like domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

A solution for the best rotation to relate two sets of vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Structure of papain refined at 1.65 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calcium-activated proteolysis as a therapeutic target in cerebrovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

EF-hand calcium-binding proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Dissociation of m-calpain subunits occurs after autolysis of the N-terminus of the catalytic subunit, and is not required for activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

AMoRe: an automated package for molecular replacement

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Dissociation and aggregation of calpain in the presence of calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

C2-domains, structure and function of a universal Ca2+-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calcium, protease action, and the regulation of the cell cycle.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

The structure of calpain.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Structure and physiological function of calpains

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

The calpain cascade. Mu-calpain activates m-calpain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Domain III of calpain is a ca2+-regulated phospholipid-binding domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calpain and caspase: can you tell the difference?

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calpain inhibition: an overview of its therapeutic potential

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

Calpain dissociates into subunits in the presence of calcium ions

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021

The calpain small subunit gene is essential: its inactivation results in embryonic lethality.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2802%2900659-1

7 January 2021