(Q27641016)

GeneDB

bifunctional dihydrofolate reductase-thymidylate synthase, putative

10 September 2018

1 reference

24 September 2018

0 references

bifunctional dihydrofolate reductase-thymidylate synthase, putative

1 reference

19 December 2018

7

Malcolm D Walkinshaw

0 references

Jirundon Yuvaniyama

object named as

Jirundon Yuvaniyama

1

0 references

Yongyuth Yuthavong

object named as

Yongyuth Yuthavong

Sumalee Kamchonwongpaisan

8

0 references

3

object named as

Sumalee Kamchonwongpaisan

0 references

author name string

Penchit Chitnumsub

2

0 references

Jarunee Vanichtanankul

4

0 references

Worachart Sirawaraporn

5

0 references

Paul Taylor

Nature structural biology

6

0 references

publication date

May 2003

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published in

0 references

volume

10

0 references

issue

5

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page(s)

357-65

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cites work

Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

1 reference

Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria

31 March 2020

1 reference

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

31 March 2020

1 reference

Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria

31 March 2020

1 reference

Antifolate-resistant mutants of Plasmodium falciparum dihydrofolate reductase

31 March 2020

1 reference

PS-15: a potent, orally active antimalarial from a new class of folic acid antagonists.

31 March 2020

1 reference

Dihydrofolate reductase: thymidylate synthase, a bifunctional polypeptide from Crithidia fasciculata

31 March 2020

1 reference

Molecular cloning and sequence analysis of the Plasmodium falciparum dihydrofolate reductase-thymidylate synthase gene

31 March 2020

1 reference

The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites

31 March 2020

1 reference

Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase

31 March 2020

1 reference

Towards an understanding of drug resistance in malaria: three-dimensional structure of Plasmodium falciparum dihydrofolate reductase by homology building

31 March 2020

1 reference

Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance

31 March 2020

1 reference

Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria.

31 March 2020

1 reference

Divergent regulation of dihydrofolate reductase between malaria parasite and human host

31 March 2020

1 reference

Atomic structure of thymidylate synthase: target for rational drug design

31 March 2020

1 reference

The catalytic mechanism and structure of thymidylate synthase

31 March 2020

1 reference

Essential protein-protein interactions between Plasmodium falciparum thymidylate synthase and dihydrofolate reductase domains

31 March 2020

1 reference

A bifunctional thymidylate synthetase-dihydrofolate reductase in protozoa

31 March 2020

1 reference

Proteolytic and partial sequencing studies of the bifunctional dihydrofolate reductase-thymidylate synthase from Daucus carota

31 March 2020

1 reference

Purification and characterization of the bifunctional thymidylate synthetase-dihydrofolate reductase from methotrexate-resistant Leishmania tropica.

31 March 2020

1 reference

Electrostatic channeling in the bifunctional enzyme dihydrofolate reductase-thymidylate synthase

31 March 2020

1 reference

Processing of X-ray diffraction data collected in oscillation mode

31 March 2020

1 reference

The finer things in X-ray diffraction data collection

31 March 2020

1 reference

AMoRe: an automated package for molecular replacement

31 March 2020

1 reference

Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug

31 March 2020

1 reference

X-ray crystallographic studies of Candida albicans dihydrofolate reductase. High resolution structures of the holoenzyme and an inhibited ternary complex

31 March 2020

1 reference

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

31 March 2020

1 reference

Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin

31 March 2020

1 reference

Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii

31 March 2020

1 reference

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

31 March 2020

1 reference

The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution

31 March 2020

1 reference

The crystal structure of dihydrofolate reductase from Thermotoga maritima: molecular features of thermostability

31 March 2020

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

31 March 2020

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

31 March 2020

1 reference

xdlMAPMAN and xdlDATAMAN - programs for reformatting, analysis and manipulation of biomacromolecular electron-density maps and reflection data sets

31 March 2020

1 reference

Template convolution to enhance or detect structural features in macromolecular electron-density maps

31 March 2020

1 reference

wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models

31 March 2020

1 reference

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

31 March 2020

1 reference

Primary structure of the gene encoding the bifunctional dihydrofolate reductase-thymidylate synthase of Leishmania major

31 March 2020

1 reference

Analysis of the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene sequence.

31 March 2020

1 reference

Antifolate drug selection results in duplication and rearrangement of chromosome 7 in Plasmodium chabaudi

31 March 2020

1 reference

Mechanisms of pyrimethamine resistance in two different strains of Plasmodium berghei.

31 March 2020

1 reference

The dihydrofolate reductase domain of rodent malarias: point mutations and pyrimethamine resistance

31 March 2020

1 reference

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

31 March 2020

1 reference

MOLMOL: a program for display and analysis of macromolecular structures

31 March 2020

1 reference

The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Bifunctional thymidylate synthase-dihydrofolate reductase in protozoa

1 reference