(Q27651858)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Structural basis for the catalytic mechanism of human phosphodiesterase 9 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

author name string

Mahmoud N Mansour

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Keith S Dillman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Jose R Perez

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Dennis E Danley

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Paul A Aeed

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Samuel P Simons

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Peter K Lemotte

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

language of work or name

English

0 references

publication date

29 August 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

13 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

volume

105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

page(s)

13309-13314

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

Structural insight into substrate specificity of phosphodiesterase 10

13 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Structural determinants for inhibitor specificity and selectivity in PDE2A using the wheat germ in vitro translation system

20 March 2017

1 reference

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Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Crystal structures of phosphodiesterases 4 and 5 in complex with inhibitor 3-isobutyl-1-methylxanthine suggest a conformation determinant of inhibitor selectivity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

The Crystal Structure of AMP-Bound PDE4 Suggests a Mechanism for Phosphodiesterase Catalysis,

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Three-dimensional structures of PDE4D in complex with roliprams and implication on inhibitor selectivity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Crystal structure of phosphodiesterase 4D and inhibitor complex(1)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Isolation and characterization of PDE9A, a novel human cGMP-specific phosphodiesterase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Identification and characterization of a novel family of cyclic nucleotide phosphodiesterases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Molecular mechanisms of the alterations in NMDA receptor-dependent long-term potentiation in hyperammonemia.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Multiple elements jointly determine inhibitor selectivity of cyclic nucleotide phosphodiesterases 4 and 7.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Identification and characterization of a new human type 9 cGMP-specific phosphodiesterase splice variant (PDE9A5). Differential tissue distribution and subcellular localization of PDE9A variants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Trapping reaction intermediates in macromolecular crystals for structural analyses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Observation of unstable species in enzyme-catalyzed transformations using protein crystallography

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Freeze trapping of reaction intermediates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

29 September 2017

How photons start vision

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Structure and conformation of nucleosides and nucleotides and their analogs as determined by x-ray diffraction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Rapid kinetics of second messenger formation in olfactory transduction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

Cyclic nucleotide research -- still expanding after half a century

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0708850105

Crystal structures of the catalytic domain of phosphodiesterase 4B complexed with AMP, 8-Br-AMP, and rolipram.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0708850105

First computational evidence for a catalytic bridging hydroxide ion in a phosphodiesterase active site.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0708850105

Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2533186

The mechanism of cyclic nucleotide hydrolysis in the phosphodiesterase catalytic site

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18757755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18757755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Divalent metal cation requirement and possible classification of cGMP-inhibited phosphodiesterase as a metallohydrolase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18757755

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0708850105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18757755%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

18757755

1 reference