(Q27653046)

3

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author name string

Alexander V Statsuk

1

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Dustin J Maly

2

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Miles A Fabian

4

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William H Biggs

5

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David J Lockhart

6

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Patrick P Zarrinkar

7

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Kevan M Shokat

Journal of the American Chemical Society

9

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language of work or name

English

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publication date

24 December 2008

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published in

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volume

130

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issue

51

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page(s)

17568-74

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cites work

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AKT/PKB signaling: navigating downstream

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c-Src binds to the cancer drug imatinib with an inactive Abl/c-Kit conformation and a distributed thermodynamic penalty

20 March 2017

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Large-scale characterization of HeLa cell nuclear phosphoproteins

20 March 2017

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Scansite 2.0: Proteome-wide prediction of cell signaling interactions using short sequence motifs

20 March 2017

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The protein kinase complement of the human genome

20 March 2017

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

20 March 2017

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Assembly of Cell Regulatory Systems Through Protein Interaction Domains

20 March 2017

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A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells

20 March 2017

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A quantitative analysis of kinase inhibitor selectivity

20 March 2017

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Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase

20 March 2017

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Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase

20 March 2017

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Reactions of orthophthalaldehyde with nucleophiles

20 March 2017

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Identification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activity

20 March 2017

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Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome

20 March 2017

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Global analysis of protein phosphorylation in yeast

20 March 2017

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A small molecule-kinase interaction map for clinical kinase inhibitors

7 April 2017

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

7 April 2017

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Use of an oriented peptide library to determine the optimal substrates of protein kinases

7 April 2017

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SRC family kinases as potential therapeutic targets for malignancies and immunological disorders

7 April 2017

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Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates.

29 September 2017

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Dialogue between LKB1 and AMPK: a hot topic at the cellular pole

29 September 2017

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A semisynthetic epitope for kinase substrates.

29 September 2017

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Large-scale phosphorylation analysis of mouse liver

29 September 2017

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Charging it up: global analysis of protein phosphorylation

29 September 2017

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Activation of AKT kinases in cancer: implications for therapeutic targeting

29 September 2017

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Identifying protein kinase substrates: hunting for the organ-grinder's monkeys.

29 September 2017

1 reference

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Hitting the target: emerging technologies in the search for kinase substrates

29 September 2017

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Structural basis for control by phosphorylation

29 September 2017

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

29 September 2017

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Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor

29 September 2017

1 reference

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Suicide substrates, mechanism-based enzyme inactivators: recent developments

29 September 2017

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Conversion of a tyrosine kinase protein substrate to a high affinity ligand by ATP linkage

29 September 2017

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An improved mechanism-based cross-linker for multiplexed kinase detection and inhibition in a complex proteome

2 June 2018

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A mechanism-based cross-linker for the identification of kinase-substrate pairs

27 November 2018

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Development of photo-crosslinking reagents for protein kinase-substrate interactions

27 November 2018

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Toward a pharmacophore for kinase frequent hitters

27 November 2018

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12 December 2020

Rational design and evaluation of improved o-phthalaldehyde-like fluorogenic reagents

1 reference

12 December 2020

Inactivation of yeast hexokinase by o-phthalaldehyde: evidence for the presence of a cysteine and a lysine at or near the active site

1 reference

12 December 2020

Evidence for proximal cysteine and lysine residues present at the nucleotide domain of rabbit muscle creatine kinase

1 reference

12 December 2020

p38 map kinase substrate specificity differs greatly for protein and peptide substrates

1 reference

12 December 2020