(Q28586196)

English

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome

scientific journal article

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scholarly article

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome (English)

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

phosphorylation

0 references

Serine/threonine kinase 11

1 reference

GOA release 2020-03-11

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

5

object named as

Nick Morrice

2 references

31 January 2017

Europe PubMed Central

7 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

Jérôme Boudeau

2

object named as

Jérôme Boudeau

2 references

31 January 2017

Europe PubMed Central

7 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

Agnieszka Kieloch

4

object named as

Agnieszka Kieloch

2 references

31 January 2017

Europe PubMed Central

7 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

author name string

Gopal P Sapkota

1

1 reference

Europe PubMed Central

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7 December 2019

Maria Deak

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

language of work or name

0 references

publication date

1 March 2002

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Biochemical Journal

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

362

2 references

31 January 2017

Europe PubMed Central

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7 December 2019

481-490

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

Pt 2

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

17 March 2017

Mammalian TOR: a homeostatic ATP sensor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

A motif-based profile scanning approach for genome-wide prediction of signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

The molecular basis and clinical aspects of Peutz-Jeghers syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

Peutz-Jeghers syndrome: 78-year follow-up of the original family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

Analysis of the specificity of the AMP-activated protein kinase by site-directed mutagenesis of bacterially expressed 3-hydroxy 3-methylglutaryl-CoA reductase, using a single primer variant of the unique-site-elimination method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

Analysis of p53 expression in human tumours: an antibody raised against human p53 expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

29 September 2017

MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222410

3 June 2018

Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11853558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity determinants of the checkpoint protein kinase Chk1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11853558

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3620481

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

2 references

31 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11853558%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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