(Q27658965)

6

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Mariangela Agamennone

1

object named as

Mariangela Agamennone

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Rebecca Del Conte

5

object named as

Rebecca Del Conte

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author name string

Lucia Cesari

2

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Daniela Lalli

3

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Elisa Turlizzi

4

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Alessandro Padova

The S100 family of EF-hand calcium-binding proteins: functions and pathology

8

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publication date

1 March 2010

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published in

ChemMedChem

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volume

5

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issue

3

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page(s)

428-35

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cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

Targets looking for drugs: a multistep computational protocol for the development of structure-based pharmacophores and their applications for hit discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

Intracellular and extracellular roles of S100 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

A novel calcium-sensitive switch revealed by the structure of human S100B in the calcium-bound form

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Analysis of the structure of human apo-S100B at low temperature indicates a unimodal conformational distribution is adopted by calcium-free S100 proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Structural and functional insights into RAGE activation by multimeric S100B

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

https://api.crossref.org/works/10.1002%2FCMDC.200900393

1 reference

7 January 2021

Inhibition of p53 transcriptional activity by the S100B calcium-binding protein.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

S100 proteins as cancer biomarkers with focus on S100B in malignant melanoma

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

The prognostic value of serum S100B in patients with cutaneous melanoma: a meta-analysis.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Regulation of p53 localization

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Calcium-dependent interaction of S100B with the C-terminal domain of the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

The Ca(2+)-dependent interaction of S100B(beta beta) with a peptide derived from p53

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Solution structure of calcium-bound rat S100B(betabeta) as determined by nuclear magnetic resonance spectroscopy,

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Structure of the negative regulatory domain of p53 bound to S100B(betabeta)

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Characterization of S-100b binding epitopes. Identification of a novel target, the actin capping protein, CapZ.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Identification and characterization of small molecule inhibitors of the calcium-dependent S100B-p53 tumor suppressor interaction.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

A search for inhibitors of S100B, a member of the S100 family of calcium-binding proteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Small Molecules Bound to Unique Sites in the Target Protein Binding Cleft of Calcium-Bound S100B As Characterized by Nuclear Magnetic Resonance and X-ray Crystallography

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Fragment docking to S100 proteins reveals a wide diversity of weak interaction sites.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Targeting protein-protein interactions with small molecules: challenges and perspectives for computational binding epitope detection and ligand finding

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Computational identification of inhibitors of protein-protein interactions.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Unraveling hot spots in binding interfaces: progress and challenges

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

A ‘Rule of Three’ for fragment-based lead discovery?

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Straightforward recursive partitioning model for discarding insoluble compounds in the drug discovery process.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Exploring experimental sources of multiple protein conformations in structure-based drug design.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Refining the multiple protein structure pharmacophore method: consistency across three independent HIV-1 protease models.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Development and validation of a genetic algorithm for flexible docking

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

WaterLOGSY as a method for primary NMR screening: practical aspects and range of applicability.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Theory and applications of NMR-based screening in pharmaceutical research

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

The maximal affinity of ligands

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Structure-based optimization of potent and selective inhibitors of the tyrosine kinase erythropoietin producing human hepatocellular carcinoma receptor B4 (EphB4).

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Fragment-based lead discovery: leads by design

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Improving the hit-to-lead process: data-driven assessment of drug-like and lead-like screening hits

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

A heteronuclear three-dimensional NMR experiment for measurements of small heteronuclear coupling constants in biological macromolecules

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Divalent Metal Ion Complexes of S100B in the Absence and Presence of Pentamidine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Identification by NMR of the binding surface for the histidine-containing phosphocarrier protein HPr on the N-terminal domain of enzyme I of the Escherichia coli phosphotransferase system.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Ligand efficiency: a useful metric for lead selection

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

The integration of macromolecular diffraction data

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

An approach to multi-copy search in molecular replacement

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900393

7 January 2021