(Q27660104)

5

0 references

Peter J. Tonge

object named as

Peter J Tonge

4

0 references

author name string

Sylvia R Luckner

1

0 references

Nina Liu

2

0 references

Christopher W am Ende

Journal of Biological Chemistry

3

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language of work or name

English

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publication date

7 May 2010

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published in

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volume

285

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issue

19

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page(s)

14330-7

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cites work

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Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosis

20 March 2017

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20 March 2017

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The isoniazid-NAD adduct is a slow, tight-binding inhibitor of InhA, the Mycobacterium tuberculosis enoyl reductase: adduct affinity and drug resistance

20 March 2017

1 reference

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Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan

20 March 2017

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Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate

20 March 2017

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Phasercrystallographic software

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1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis

20 March 2017

1 reference

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Mycolic acids: structure, biosynthesis and physiological functions

20 March 2017

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Triclosan targets lipid synthesis

20 March 2017

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inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

20 March 2017

1 reference

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7 April 2017

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Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors

29 September 2017

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Residence time of receptor-ligand complexes and its effect on biological function

29 September 2017

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Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway

29 September 2017

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Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis

29 September 2017

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29 September 2017

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29 September 2017

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Methotrexate, a high-affinity pseudosubstrate of dihydrofolate reductase

29 September 2017

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Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase

29 September 2017

1 reference

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Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.

21 January 2018

1 reference

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Inhibition of the bacterial enoyl reductase FabI by triclosan: a structure-reactivity analysis of FabI inhibition by triclosan analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.090373

Insight through molecular mechanics Poisson-Boltzmann surface area calculations into the binding affinity of triclosan and three analogues for FabI, the E. coli enoyl reductase.

21 January 2018

1 reference

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Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase fromMycobacterium tuberculosis†

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20200152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains ofMycobacterium tuberculosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20200152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Evaluation of enzyme inhibitors in drug discovery. A guide for medicinal chemists and pharmacologists

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20200152