(Q27661041)

2

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Mu-ya Liu

3

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Celestine Thomas

4

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Stephen R Sprang

5

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Paul C Sternweis

Journal of Biological Chemistry

6

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language of work or name

English

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publication date

2 July 2010

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published in

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volume

285

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issue

27

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page(s)

21070-81

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cites work

Recognition of the Activated States of Gα13 by the rgRGS Domain of PDZRhoGEF

1 reference

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Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)

20 March 2017

1 reference

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The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle

20 March 2017

1 reference

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Structural insights into the interaction of ROCKI with the switch regions of RhoA

20 March 2017

1 reference

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Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

20 March 2017

1 reference

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Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF

20 March 2017

1 reference

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The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG

20 March 2017

1 reference

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Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

20 March 2017

1 reference

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Electrostatics of nanosystems: application to microtubules and the ribosome

20 March 2017

1 reference

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Galpha 13 requires palmitoylation for plasma membrane localization, Rho-dependent signaling, and promotion of p115-RhoGEF membrane binding

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1

20 March 2017

1 reference

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20 March 2017

The Protein Data Bank

1 reference

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Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Crystal structure of RhoA-GDP and its functional implications

20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Rho GTPases in cell biology

20 March 2017

1 reference

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The guanine nucleotide-binding switch in three dimensions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Identification of potential mechanisms for regulation of p115 RhoGEF through analysis of endogenous and mutant forms of the exchange factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Conformation of Polypeptides and Proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Regulation of Rho guanine nucleotide exchange factors by G proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Rho GTPase-activating proteins in cell regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Molecular determinants in pleckstrin homology domains that allow specific recognition of phosphoinositides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2898337

Processing of X-ray diffraction data collected in oscillation mode

29 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122549

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122549

The Rho guanine nucleotide exchange factor Lsc homo-oligomerizes and is negatively regulated through domains in its carboxyl terminus that are absent in novel splenic isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122549

Differences in Galpha12- and Galpha13-mediated plasma membrane recruitment of p115-RhoGEF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122549

Improved Fourier coefficients for maps using phases from partial structures with errors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122549

Crystal structure of Rac1 bound to its effector phospholipase C-β2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.122549

Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20430886

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An electrostatic steering mechanism of Cdc42 recognition by Wiskott-Aldrich syndrome proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20430886