(Q27661380)

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Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation

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Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation (English)

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James Henderson Naismith

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James H Naismith

10

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David J Clarke

7

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Dominic J Campopiano

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Dominic J Campopiano

11

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author name string

Jonathan Lowther

1

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Beverley A Yard

2

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Kenneth A Johnson

3

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Lester G Carter

4

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Venugopal T Bhat

5

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Marine C C Raman

6

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Britta Ramakers

8

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Stephen A McMahon

9

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publication date

September 2010

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Molecular BioSystems

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6

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9

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1682-93

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THE ENZYMATIC SYNTHESIS OF D-ALANYL-D-ALANINE. 3. ON THE INHIBITION OF D-ALANYL-D-ALANINE SYNTHETASE BY THE ANTIBIOTIC D-CYCLOSERINE

1 reference

https://pubmed.ncbi.nlm.nih.gov/20445930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of sphingolipid synthesis by cycloserine in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20445930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of inhibitors of serine palmitoyltransferase (SPT), a key enzyme in sphingolipid biosynthesis, in intact cells. A novel evaluation system using an SPT-defective mammalian cell mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/20445930

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cycloserine dimer hydrolysis and its equilibration with cycloserine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20445930

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based on heuristic

inferred from PubMed ID database lookup

Cycloserine. I. A preliminary report

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https://pubmed.ncbi.nlm.nih.gov/20445930

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based on heuristic

inferred from PubMed ID database lookup

D-Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20445930

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On the mechanism of action of antibiotics which act as irreversible enzyme inhibitors

1 reference

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based on heuristic

inferred from PubMed ID database lookup

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10.1039/C003743E

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