(Q27662522)

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Structural Characterization of the Mycobacterium tuberculosis Biotin Biosynthesis Enzymes 7,8-Diaminopelargonic Acid Synthase and Dethiobiotin Synthetase,

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scholarly article

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Structural Characterization of the Mycobacterium tuberculosis Biotin Biosynthesis Enzymes 7,8-Diaminopelargonic Acid Synthase and Dethiobiotin Synthetase, (English)

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Mycobacterium tuberculosis

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object named as

Richard E Lee

3

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object named as

Eric J Rubin

4

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author name string

Sanghamitra Dey

1

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James M Lane

2

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James C Sacchettini

5

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language of work or name

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publication date

10 August 2010

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49

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31

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6746-60

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Application of a Theory of Enzyme Specificity to Protein Synthesis

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20 March 2017

Biotin synthesis in plants. The first committed step of the pathway is catalyzed by a cytosolic 7-keto-8-aminopelargonic acid synthase

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20 March 2017

Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition

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20 March 2017

Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis

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20 March 2017

Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin

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A Side Reaction of Alanine Racemase: Transamination of Cycloserine,

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Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding

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20 March 2017

The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation

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20 March 2017

Structural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin

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20 March 2017

Concanavalin A in a dimeric crystal form: revisiting structural accuracy and molecular flexibility

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20 March 2017

Crystal structure of diaminopelargonic acid synthase: evolutionary relationships between pyridoxal-5'-phosphate-dependent enzymes

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20 March 2017

Structure of dethiobiotin synthetase at 0.97 A resolution

1 reference

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20 March 2017

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

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20 March 2017

Snapshot of a phosphorylated substrate intermediate by kinetic crystallography

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20 March 2017

Human ornithine aminotransferase complexed with L-canaline and gabaculine: structural basis for substrate recognition

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20 March 2017

Crystal structure of glutamate-1-semialdehyde aminomutase: an alpha2-dimeric vitamin B6-dependent enzyme with asymmetry in structure and active site reactivity

1 reference

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20 March 2017

Crystal structures of Escherichia coli aspartate aminotransferase in two conformations. Comparison of an unliganded open and two liganded closed forms

1 reference

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20 March 2017

Crystalline mitochondrial aspartate aminotransferase exists in only two conformations

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20 March 2017

Crystal structure of an ATP-dependent carboxylase, dethiobiotin synthetase, at 1.65 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503319

20 March 2017

Refined crystal structures of unligated adenylosuccinate synthetase from Escherichia coli

1 reference

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20 March 2017

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

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20 March 2017

Likelihood-enhanced fast rotation functions

1 reference

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20 March 2017

The finer things in X-ray diffraction data collection

2 references

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20 March 2017

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29 September 2017

XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

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20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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20 March 2017

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

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20 March 2017

Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake

1 reference

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20 March 2017

Biosynthesis of 7, 8-diaminopelargonic acid from 7-keto-8-aminopelargonic acid and S-adenosyl-L-methionine. The kinetics of the reaction

1 reference

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20 March 2017

Purification and properties of 7, 8-diaminopelargonic acid aminotransferase

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20 March 2017

7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target. Characterization and inhibition studies

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20 March 2017

Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling

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20 March 2017

Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis

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20 March 2017

Genetic requirements for mycobacterial survival during infection

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7 April 2017

Direct evidence for a glutamate switch necessary for substrate recognition: crystal structures of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv

1 reference

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29 September 2017

Dual substrate recognition of aminotransferases

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29 September 2017

M. tuberculosis persistence, latency, and drug tolerance

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29 September 2017

Starvation Survival Response of Mycobacterium tuberculosis

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29 September 2017

Mutants of Mycobacterium smegmatis impaired in stationary-phase survival.

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29 September 2017

Biosynthesis of diaminopimelate, the precursor of lysine and a component of peptidoglycan, is an essential function of Mycobacterium smegmatis.

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29 September 2017

The biotin-dependent enzymes

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29 September 2017

61 Dethiobiotin synthetase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3503319

29 September 2017

Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis

1 reference

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Active site mutants of Escherichia coli dethiobiotin synthetase: effects of mutations on enzyme catalytic and structural properties.

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Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

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2 June 2018

Active site model for gamma-aminobutyrate aminotransferase explains substrate specificity and inhibitor reactivities

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2 June 2018

Biological studies of amiclenomycin

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2 June 2018

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Studies on a new amino acid antibiotic, amiclenomycin.

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The mechanism of 7,8-diaminopelargonate synthase; the role of S-adenosylmethionine as the amino donor

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27 November 2018

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12 December 2020

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https://pubmed.ncbi.nlm.nih.gov/20565114

12 December 2020

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Spectral and kinetic characterization of 7,8-diaminopelargonic acid synthase from Mycobacterium tuberculosis

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https://pubmed.ncbi.nlm.nih.gov/20565114

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actithiazic acid. IV. Pharmacological studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20565114

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https://pubmed.ncbi.nlm.nih.gov/20565114

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based on heuristic

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https://pubmed.ncbi.nlm.nih.gov/20565114

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI902097J

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