Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q27667285)
Watch
English
Small-Molecule Ligands of Methyl-Lysine Binding Proteins
scientific article
In more languages
edit
Statements
instance of
scholarly article
0 references
title
Small-Molecule Ligands of Methyl-Lysine Binding Proteins
(English)
0 references
main subject
drug discovery
0 references
author
Guillermo Senisterra
series ordinal
9
0 references
Masoud Vedadi
series ordinal
10
0 references
Peter J. Brown
object named as
Peter J Brown
series ordinal
12
0 references
Cheryl Arrowsmith
object named as
Cheryl H Arrowsmith
series ordinal
13
0 references
author name string
J Martin Herold
series ordinal
1
0 references
Tim J Wigle
series ordinal
2
0 references
Jacqueline L Norris
series ordinal
3
0 references
Robert Lam
series ordinal
4
0 references
Victoria K Korboukh
series ordinal
5
0 references
Cen Gao
series ordinal
6
0 references
Lindsey A Ingerman
series ordinal
7
0 references
Dmitri B Kireev
series ordinal
8
0 references
Ashutosh Tripathy
series ordinal
11
0 references
Jian Jin
series ordinal
14
0 references
William P Janzen
series ordinal
15
0 references
Stephen V Frye
series ordinal
16
0 references
language of work or name
English
0 references
publication date
14 April 2011
0 references
published in
Journal of Medicinal Chemistry
0 references
volume
54
0 references
issue
7
0 references
page(s)
2504-11
0 references
cites work
Selective inhibition of BET bromodomains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Methylation of the retinoblastoma tumor suppressor by SMYD2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Structural studies of a four-MBT repeat protein MBTD1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Molecular recognition of histone lysine methylation by the Polycomb group repressor dSfmbt
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
An operational definition of epigenetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
L3MBTL1 recognition of mono- and dimethylated histones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
L3MBTL1, a histone-methylation-dependent chromatin lock
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
SMART, a simple modular architecture research tool: identification of signaling domains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Coot: model-building tools for molecular graphics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
The CCP4 suite: programs for protein crystallography
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
How to measure and predict the molar absorption coefficient of a protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
20 March 2017
Rapid measurement of binding constants and heats of binding using a new titration calorimeter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
7 April 2017
The mammalian epigenome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
7 April 2017
L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Identification of non-peptide malignant brain tumor (MBT) repeat antagonists by virtual screening of commercially available compounds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Loss, mutation and deregulation of L3MBTL4 in breast cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Biophysical characterization of recombinant proteins: a key to higher structural genomics success
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
The art of the chemical probe
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Pharmacophore screening of the protein data bank for specific binding site chemistry.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
MBT domain proteins in development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Protein methyltransferases as a target class for drug discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Stem cells in drug discovery, tissue engineering, and regenerative medicine: emerging opportunities and challenges
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Structure and function of histone methylation binding proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Role of histone modifications in defining chromatin structure and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Sensing the heat: the application of isothermal titration calorimetry to thermodynamic studies of biomolecular interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
29 September 2017
Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3109722
retrieved
2 June 2018
Ligand binding efficiency: trends, physical basis, and implications
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21417280
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Finding Inspiration in the Protein Data Bank to Chemically Antagonize Readers of the Histone Code
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21417280
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Processing of X-ray diffraction data collected in oscillation mode
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21417280
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/JM200045V
0 references
PMC publication ID
3109722
0 references
PubMed publication ID
21417280
0 references
ResearchGate publication ID
50590981
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
