(Q27670560)

8

0 references

David Langley

6

object named as

David Langley

0 references

author name string

Kip Dudgeon

1

0 references

Iris Kokmeijer

3

0 references

Jessica Stolp

5

0 references

Daniela Stock

7

0 references

Peter Schofield

Proceedings of the National Academy of Sciences of the United States of America

4

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language of work or name

English

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publication date

3 July 2012

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published in

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volume

109

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issue

27

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page(s)

10879-84

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cites work

Variants of the antibody herceptin that interact with HER2 and VEGF at the antigen binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Humanization of an anti-p185HER2 antibody for human cancer therapy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Naturally occurring antibodies devoid of light chains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Replacing the complementarity-determining regions in a human antibody with those from a mouse

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Tapping diversity lost in transformations--in vitro amplification of ligation reactions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Aggregation, stability, and formulation of human antibody therapeutics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Development trends for human monoclonal antibody therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Sequence determinants of protein aggregation in human VH domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Antibody therapeutics, antibody engineering, and the merits of protein stability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Repertoires of aggregation-resistant human antibody domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Supercharging proteins can impart unusual resilience

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Engineered antibody fragments and the rise of single domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Immunogenicity of engineered antibodies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Rationalization of the effects of mutations on peptide and protein aggregation rates.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Structure-based improvement of the biophysical properties of immunoglobulin VH domains with a generalizable approach

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Biophysical properties of human antibody variable domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Sequence and structure of VH domain from naturally occurring camel heavy chain immunoglobulins lacking light chains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

All individual domains of staphylococcal protein A show Fab binding.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Antibody-antigen interactions: contact analysis and binding site topography.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

A directory of human germ-line V kappa segments reveals a strong bias in their usage

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Representation of rearranged VH gene segments in the human adult antibody repertoire

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390889

Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

Potential aggregation prone regions in biotherapeutics: A survey of commercial monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

Thermodynamic analysis of an antibody functional epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

The Imprint of Somatic Hypermutation on the Repertoire of Human Germline V Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

Biophysical Properties of Camelid VHHDomains Compared to Those of Human VH3 Domains†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

Engineering Aggregation Resistance in IgG by Two Independent Mechanisms: Lessons from Comparison of Pichia pastoris and Mammalian Cell Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202866109

Monoclonal antibody successes in the clinic

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22745168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aggregation-resistant domain antibodies selected on phage by heat denaturation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22745168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Canonical structures for the hypervariable regions of immunoglobulins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22745168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1202866109

1 reference

release_qhrzkoxikfbupky2wawnajvm3q

0 references

0 references

2891080

1 reference

1 reference

2891080

PubMed publication ID

22745168

1 reference