(Q27671971)

4

0 references

Jeffery W. Kelly

8

object named as

Jeffery W Kelly

0 references

Mamoun Alhamadsheh

1

object named as

Mamoun M Alhamadsheh

0 references

author name string

Stephen Connelly

2

0 references

Ahryon Cho

3

0 references

Evan T Powers

5

0 references

Dorothy W Pan

6

0 references

Ian A Wilson

7

0 references

Isabella A Graef

Science Translational Medicine

9

0 references

language of work or name

English

0 references

publication date

24 August 2011

0 references

published in

0 references

volume

3

0 references

issue

97

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page(s)

97ra81

0 references

cites work

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20 March 2017

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Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials

20 March 2017

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Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

20 March 2017

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Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis

20 March 2017

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Structure of a complex of two plasma proteins: transthyretin and retinol-binding protein

20 March 2017

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Fibril in senile systemic amyloidosis is derived from normal transthyretin

20 March 2017

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

20 March 2017

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Folding proteins in fatal ways

20 March 2017

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Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

7 April 2017

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Transthyretin-related amyloidoses and the heart: a clinical overview

29 September 2017

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Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies

29 September 2017

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29 September 2017

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Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses

29 September 2017

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Cardiac amyloidosis: approaches to diagnosis and management

29 September 2017

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Amyloidosis and the heart: a comprehensive review

29 September 2017

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Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses.

29 September 2017

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Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses

29 September 2017

1 reference

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Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis

29 September 2017

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Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same?

29 September 2017

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29 September 2017

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Clinical consequences of cytochrome P450 2C9 polymorphisms

29 September 2017

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29 September 2017

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Non-steroidal anti-inflammatory drugs and the continuum of renal dysfunction

29 September 2017

1 reference

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Prevention of transthyretin amyloid disease by changing protein misfolding energetics.

29 September 2017

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Direct measurement of protein binding energetics by isothermal titration calorimetry

29 September 2017

1 reference

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The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis

29 September 2017

1 reference

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Trans-suppression of misfolding in an amyloid disease.

29 September 2017

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Pathogenesis of NSAID-induced gastroduodenal mucosal injury

29 September 2017

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Risk of cardiovascular events associated with selective COX-2 inhibitors

29 September 2017

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Early liver transplantation is essential for familial amyloidotic polyneuropathy patients' quality of life

29 September 2017

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Consumption of NSAIDs and the development of congestive heart failure in elderly patients: an underrecognized public health problem.

29 September 2017

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Cyclooxygenase 2 inhibitors: discovery, selectivity and the future

29 September 2017

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Analysis of amyloid deposition in a transgenic mouse model of homozygous familial amyloidotic polyneuropathy

29 September 2017

1 reference

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Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

Transthyretin (prealbumin) in health and disease: nutritional implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

A homozygous transthyretin variant associated with senile systemic amyloidosis: evidence for a late-onset disease of genetic etiology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

Partial denaturation of transthyretin is sufficient for amyloid fibril formation in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

29 September 2017

The systemic amyloidoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

Systemic amyloidosis in transgenic mice carrying the human mutant transthyretin (Met30) gene. Pathologic similarity to human familial amyloidotic polyneuropathy, type I.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227540

The biological and chemical basis for tissue-selective amyloid disease

2 June 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

Kinetic stabilization of an oligomeric protein by a single ligand binding event

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

Heart transplantation for homozygous familial transthyretin (TTR) V122I cardiac amyloidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

Tabulation of human transthyretin (TTR) variants, 2003

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3002473

Change in structure of the N-terminal region of transthyretin produces change in affinity of transthyretin to T4 and T3

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21865539

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.3002473

1 reference

1 reference

1 reference

PubMed publication ID

21865539

1 reference