(Q27675290)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

title

Structural analyses of a constitutively active mutant of exchange protein directly activated by cAMP (English)

1 reference

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18 February 2020

1

1 reference

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18 February 2020

author name string

Sheng Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Tamara Tsalkova

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Fang C Mei

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Tong Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Virgil L Woods

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

Xiaodong Cheng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

language of work or name

English

0 references

publication date

26 November 2012

1 reference

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18 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

7

1 reference

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18 February 2020

issue

11

1 reference

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18 February 2020

page(s)

e49932

1 reference

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Creative Commons Attribution 4.0 International

18 February 2020

copyright license

start time

26 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

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The SWISS-MODEL Repository and associated resources

20 March 2017

1 reference

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Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

20 March 2017

1 reference

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Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

20 March 2017

1 reference

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A family of cAMP-binding proteins that directly activate Rap1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Features and development of Coot

20 March 2017

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Version 1.2 of the Crystallography and NMR system

20 March 2017

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Isoform-specific antagonists of exchange proteins directly activated by cAMP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Use of knowledge-based restraints in phenix.refine to improve macromolecular refinement at low resolution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Automated protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Role of dynamics in the autoinhibition and activation of the exchange protein directly activated by cyclic AMP (EPAC)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Mechanism of intracellular cAMP sensor Epac2 activation: cAMP-induced conformational changes identified by amide hydrogen/deuterium exchange mass spectrometry (DXMS).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Mapping allostery through the covariance analysis of NMR chemical shifts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Mechanism of Epac activation: structural and functional analyses of Epac2 hinge mutants with constitutive and reduced activities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Dissecting the mechanism of Epac activation via hydrogen-deuterium exchange FT-IR and structural modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Rapid refinement of crystallographic protein construct definition employing enhanced hydrogen/deuterium exchange MS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3506601

Structural dynamics in the activation of Epac.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049932

The crystal structure of the Venezuelan equine encephalitis alphavirus nsP2 protease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049932

Mapping intersubunit interactions of the regulatory subunit (RIalpha) in the type I holoenzyme of protein kinase A by amide hydrogen/deuterium exchange mass spectrometry (DXMS).

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0049932

Conformational analysis of Epac activation using amide hydrogen/deuterium exchange mass spectrometry

21 January 2018

1 reference

12 December 2020

Structure of a glutathione conjugate bound to the active site of aldose reductase

1 reference

12 December 2020

Structure of oligomeric beta B2-crystallin: an application of the T2 translation function to an asymmetric unit containing two dimers

1 reference

12 December 2020

Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0049932

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

23189173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23189173%20AND%20SRC:MED&resulttype=core&format=json