(Q27675410)

1

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Won-Chan Choi

2

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Stacy Lee

3

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Jungwon Hwang

4

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Eunha Hwang

5

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Koushik Guchhait

6

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Juergen Haas

7

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Zsolt Toth

8

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Tae-Kwang Oh

10

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Myung Hee Kim

11

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Jae U Jung

Nature Structural & Molecular Biology

12

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publication date

6 November 2011

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published in

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volume

18

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issue

12

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page(s)

1336-44

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cites work

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In situ proteolysis for protein crystallization and structure determination

20 March 2017

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Molecular recognition of p53 and MDM2 by USP7/HAUSP

20 March 2017

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Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway

20 March 2017

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Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

20 March 2017

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20 March 2017

The Protein Data Bank

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A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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Main-chain bond lengths and bond angles in protein structures

20 March 2017

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Breaking the chains: structure and function of the deubiquitinases

20 March 2017

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Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization

20 March 2017

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Tumour suppression: disruption of HAUSP gene stabilizes p53

20 March 2017

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

20 March 2017

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7 April 2017

Modes of p53 regulation

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Restoration of p53 function leads to tumour regression in vivo

7 April 2017

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Reactivation of p53: from peptides to small molecules.

7 April 2017

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DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination

29 September 2017

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Immune Evasion by Kaposi‘s Sarcoma-Associated Herpesvirus

29 September 2017

1 reference

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The p53 orchestra: Mdm2 and Mdmx set the tone

29 September 2017

1 reference

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Viral interferon regulatory factors

29 September 2017

1 reference

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The multiple levels of regulation by p53 ubiquitination

29 September 2017

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Role of amphipathic helix of a herpesviral protein in membrane deformation and T cell receptor downregulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies

29 September 2017

1 reference

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Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator.

29 September 2017

1 reference

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TAT transduction: the molecular mechanism and therapeutic prospects

29 September 2017

1 reference

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Modeling the therapeutic efficacy of p53 restoration in tumors

29 September 2017

1 reference

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Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus lymphomas: implications for therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

NF-kappaB is essential for the progression of KSHV- and EBV-infected lymphomas in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Herpesviral protein networks and their interaction with the human proteome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Novel antisense anti-MDM2 mixed-backbone oligonucleotides: proof of principle, in vitro and in vivo activities, and mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

HAUSP is required for p53 destabilization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Protein profiling with Epstein-Barr nuclear antigen-1 reveals an interaction with the herpesvirus-associated ubiquitin-specific protease HAUSP/USP7.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Expression of p53 and human herpesvirus-8 (HHV-8)-encoded latency-associated nuclear antigen with inhibition of apoptosis in HHV-8-associated malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

Hemi- or homozygosity: a requirement for some but not other p53 mutant proteins to accumulate and exert a pathogenetic effect.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3589550

The p53--Mdm2--HAUSP complex is involved in p53 stabilization by HAUSP.

2 June 2018

1 reference

Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.

21 January 2018

1 reference

FLIP-mediated autophagy regulation in cell death control

21 January 2018

1 reference

Inhibition of HHV-8/KSHV infected primary effusion lymphomas in NOD/SCID mice by azidothymidine and interferon-alpha.

21 January 2018

1 reference

Control of DNMT1 abundance in epigenetic inheritance by acetylation, ubiquitylation, and the histone code.

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

MOLREP: an Automated Program for Molecular Replacement

21 January 2018

1 reference

Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22056774