(Q24303581)

GOA release 2020-03-11

5

Huib Ovaa

Huib

Ovaa

1 reference

9 December 2023

Madelon M Maurice

2

Madelon M

Maurice

1 reference

9 December 2023

Chris Boutell

3

Chris

Boutell

1 reference

9 December 2023

Erik Meulmeester

1

Erik

Meulmeester

1 reference

9 December 2023

Amina F A S Teunisse

4

Amina F A S

Teunisse

1 reference

9 December 2023

Tsion E Abraham

6

Tsion E

Abraham

1 reference

9 December 2023

Roeland W Dirks

7

Roeland W

Dirks

1 reference

9 December 2023

Aart G Jochemsen

8

Aart G

Signaling to p53: breaking the MDM2-p53 circuit

Jochemsen

1 reference

9 December 2023

language of work or name

English

0 references

publication date

27 May 2005

0 references

published in

Molecular Cell

0 references

volume

18

0 references

page(s)

565-76

0 references

issue

5

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

The p53 and Mdm2 families in cancer.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

A dynamic role of HAUSP in the p53-Mdm2 pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Tumour suppression: disruption of HAUSP gene stabilizes p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Comparative study of the p53-mdm2 and p53-MDMX interfaces

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Hdmx protein stability is regulated by the ubiquitin ligase activity of Mdm2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

The herpes simplex virus type 1 (HSV-1) regulatory protein ICP0 interacts with and Ubiquitinates p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

DNA damage-induced MDMX degradation is mediated by MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

High expression of the HMG box factor sox-13 in arterial walls during embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

MdmX protects p53 from Mdm2-mediated degradation

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Critical contribution of the MDM2 acidic domain to p53 ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

MDM2 promotes ubiquitination and degradation of MDMX

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLCEL.2005.04.024

7 January 2021