(Q27675449)

English

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus [...]

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231439%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231439%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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20 February 2020

Andrew D. Mesecar

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20 February 2020

Craig W. Lindsley

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20 February 2020

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20 February 2020

Anna M. Mielech

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20 February 2020

Valerie Grum-Tokars

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20 February 2020

Yahira M Baez-Santos

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20 February 2020

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Jon Jacobs

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20 February 2020

Ya Zhou

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20 February 2020

Mark Turlington

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20 February 2020

S Adrian Saldanha

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20 February 2020

Peter Chase

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20 February 2020

Aimee Eggler

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20 February 2020

Eric S Dawson

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20 February 2020

Peter Hodder

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20 February 2020

Shaun R Stauffer

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20 February 2020

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3 January 2013

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20 February 2020

Journal of Medicinal Chemistry

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20 February 2020

56

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20 February 2020

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20 February 2020

534-546

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20 February 2020

Structure-based design, synthesis, and evaluation of peptide-mimetic SARS 3CL protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Antiviral Drug Design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

Coronavirus main proteinase (3CLpro) structure: basis for design of anti-SARS drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

The Protein Data Bank

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

7 April 2017

Ligand efficiency: a useful metric for lead selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

7 April 2017

A novel coronavirus associated with severe acute respiratory syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

7 April 2017

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

7 April 2017

Human Coronaviruses HCoV-NL63 and HCoV-HKU1 in Hospitalized Children with Acute Respiratory Infections in Beijing, China

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Virtual screening identification of novel severe acute respiratory syndrome 3C-like protease inhibitors and in vitro confirmation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Human coronavirus NL63: a clinically important virus?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Profiling of substrate specificity of SARS-CoV 3CL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Evaluating the 3C-like protease activity of SARS-Coronavirus: recommendations for standardized assays for drug discovery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Recent developments in the virology and antiviral research of severe acute respiratory syndrome coronavirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Drug design targeting the main protease, the Achilles' heel of coronaviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

The novel human coronaviruses NL63 and HKU1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Targeting proteases: successes, failures and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

The papain-like protease of severe acute respiratory syndrome coronavirus has deubiquitinating activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Structural insights into SARS coronavirus proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3569073

29 September 2017

Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro

1 reference

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29 September 2017

A molecular viewer for the analysis of TLS rigid-body motion in macromolecules

1 reference

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29 September 2017

Molecular biology of severe acute respiratory syndrome coronavirus

1 reference

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29 September 2017

Small molecules targeting severe acute respiratory syndrome human coronavirus

1 reference

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29 September 2017

Biosynthesis, Purification, and Substrate Specificity of Severe Acute Respiratory Syndrome Coronavirus 3C-like Proteinase

1 reference

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29 September 2017

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

1 reference

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29 September 2017

Viral replicase gene products suffice for coronavirus discontinuous transcription

1 reference

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29 September 2017

Multicomponent Reactions with Isocyanides.

1 reference

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29 September 2017

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1 reference

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1 reference

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1 reference

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Aryl methylene ketones and fluorinated methylene ketones as reversible inhibitors for severe acute respiratory syndrome (SARS) 3C-like proteinase

1 reference

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27 November 2018

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1 reference

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1 reference

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Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors

1 reference

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27 November 2018

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1 reference

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27 November 2018

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1 reference

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27 November 2018

The substrate specificity of SARS coronavirus 3C-like proteinase

1 reference

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27 November 2018

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1 reference

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27 November 2018

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1 reference

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1 reference

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27 November 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23231439

12 December 2020

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10.1021/JM301580N

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20 February 2020

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https://api.fatcat.wiki/v0/release/gbbsd6qxabavffqy5sz2fgzj6u

24 November 2022

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

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20 February 2020

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23231439%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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