(Q27675738)

GOA release 2020-03-11

heme binding

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

1 reference

4

Irina A Pikuleva

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author name string

Natalia Mast

series ordinal

1

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Wenchao Zheng

series ordinal

2

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C David Stout

series ordinal

3

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language of work or name

English

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publication date

15 February 2013

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published in

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volume

288

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issue

7

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page(s)

4613-24

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cites work

In Silico and Intuitive Predictions of CYP46A1 Inhibition by Marketed Drugs with Subsequent Enzyme Crystallization in Complex with Fluvoxamine

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Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1

20 March 2017

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Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophore

20 March 2017

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Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain

20 March 2017

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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain

20 March 2017

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Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

20 March 2017

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Structural basis for antagonism and resistance of bicalutamide in prostate cancer

20 March 2017

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cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

20 March 2017

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Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

20 March 2017

1 reference

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High-resolution crystal structure of cytochrome P450cam

20 March 2017

1 reference

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Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam

20 March 2017

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20 March 2017

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Phasercrystallographic software

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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20 March 2017

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Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain

20 March 2017

1 reference

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Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

20 March 2017

1 reference

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Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

20 March 2017

1 reference

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THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE

20 March 2017

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Mechanism of androgen receptor antagonism by bicalutamide in the treatment of prostate cancer

7 April 2017

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Cholestenoic Acid is an important elimination product of cholesterol in the retina: comparison of retinal cholesterol metabolism with that in the brain.

29 September 2017

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The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo

29 September 2017

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Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase

29 September 2017

1 reference

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New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection

29 September 2017

1 reference

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Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1

29 September 2017

1 reference

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Cytochrome p450 and chemical toxicology

29 September 2017

1 reference

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Brain cholesterol turnover required for geranylgeraniol production and learning in mice

29 September 2017

1 reference

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Structure and chemistry of cytochrome P450.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576067

Role of itraconazole metabolites in CYP3A4 inhibition

29 September 2017

1 reference

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Correlation of type I, type II, and reverse type I difference spectra with absolute changes in spin state of hepatic microsomal cytochrome P-450 iron from five mammalian species

29 September 2017

1 reference

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The kinetic mechanism for cytochrome P450 metabolism of type II binding compounds: evidence supporting direct reduction

29 September 2017

1 reference

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Spectral studies of drug interaction with hepatic microsomal cytochrome.

2 June 2018

1 reference

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Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH

2 June 2018

1 reference

12 December 2020

Enantioselective binding of Casodex to the androgen receptor

1 reference

12 December 2020

Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode

1 reference

12 December 2020

Spectroscopic investigations of ferric cytochrome P-450-CAM ligand complexes. Identification of the ligand trans to cysteinate in the native enzyme

1 reference

12 December 2020

Conformational polymorphism in bicalutamide

1 reference

12 December 2020

Formation of low spin complexes of ferric cytochrome P-450-CAM with anionic ligands. Spin state and ligand affinity comparison to myoglobin

1 reference

12 December 2020

Cytochrome P-450 difference spectra: effect of chemical structure on type II spectra in mouse hepatic microsomes

1 reference

12 December 2020

The influence of oxygen donor ligation on the spectroscopic properties of ferric cytochrome P-450: ester, ether and ketone co-ordination to the haem iron

1 reference

12 December 2020

Drug interaction with hepatic microsomal cytochrome

1 reference

12 December 2020

Hierarchy of supramolecular synthons: persistent hydroxyl...pyridine hydrogen bonds in cocrystals that contain a cyano acceptor

1 reference

12 December 2020