(Q27675990)

14

0 references

Apirat Chaikuad

6

Apirat Chaikuad

0 references

James W. Murray

James W Murray

4

0 references

Opher Gileadi

Opher Gileadi

12

0 references

Stefan Knapp

Stefan Knapp

Chancievan Thangaratnarajah

13

0 references

Chancievan Thangaratnarajah

8

0 references

author name string

Peter Canning

1

0 references

Christopher D O Cooper

2

0 references

Ashley C W Pike

5

0 references

Tracy Keates

7

0 references

Viktorija Hojzan

9

0 references

Vikram Ayinampudi

10

0 references

Brian D Marsden

11

0 references

Alex N Bullock

Journal of Biological Chemistry

15

0 references

language of work or name

English

0 references

publication date

15 March 2013

0 references

published in

0 references

volume

288

0 references

page(s)

7803-14

0 references

issue

11

0 references

cites work

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Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

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BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer

20 March 2017

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Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

20 March 2017

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Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase

20 March 2017

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Ubiquitin-dependent regulation of COPII coat size and function

20 March 2017

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The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation

20 March 2017

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A Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In Vivo

20 March 2017

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 March 2017

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MolProbity: all-atom structure validation for macromolecular crystallography

20 March 2017

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Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases

20 March 2017

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Novel -Propeller of the BTB-Kelch Protein Krp1 Provides a Binding Site for Lasp-1 That Is Necessary for Pseudopodial Extension

20 March 2017

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Mutations in a BTB-Kelch protein, KLHL7, cause autosomal-dominant retinitis pigmentosa

20 March 2017

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Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways

20 March 2017

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Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation

20 March 2017

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BTB Protein KLHL12 targets the dopamine D4 receptor for ubiquitination by a Cul3-based E3 ligase

20 March 2017

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Structure of the SOCS4-ElonginB/C Complex Reveals a Distinct SOCS Box Interface and the Molecular Basis for SOCS-Dependent EGFR Degradation

20 March 2017

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Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response

20 March 2017

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Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination

20 March 2017

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Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

20 March 2017

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Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

20 March 2017

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Sequence and structural analysis of BTB domain proteins

20 March 2017

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Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

20 March 2017

1 reference

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In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

20 March 2017

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Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Multiple sequence alignment with the Clustal series of programs

20 March 2017

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Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

20 March 2017

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

20 March 2017

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Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

20 March 2017

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Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

20 March 2017

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20 March 2017

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Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

29 September 2017

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Crystal structure of the BTB domain from PLZF

20 March 2017

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REFMAC5 for the refinement of macromolecular crystal structures

20 March 2017

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Features and development of Coot

20 March 2017

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20 March 2017

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Phasercrystallographic software

20 March 2017

1 reference

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Version 1.2 of the Crystallography and NMR system

20 March 2017

1 reference

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Inference of macromolecular assemblies from crystalline state

20 March 2017

1 reference

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Automated structure solution with autoSHARP

20 March 2017

1 reference

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The Buccaneer software for automated model building. 1. Tracing protein chains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Scaling and assessment of data quality

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

20 March 2017

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20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

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Function and regulation of cullin-RING ubiquitin ligases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

20 March 2017

1 reference

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Crystal structure of the Kelch domain of human Keap1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Recent developments in classical density modification

20 March 2017

1 reference

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Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer

7 April 2017

1 reference

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Structural assembly of cullin-RING ubiquitin ligase complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Kelch-like homologue 9 mutation is associated with an early onset autosomal dominant distal myopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

High-throughput production of human proteins for crystallization: the SGC experience.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Multimodal activation of the ubiquitin ligase SCF by Nedd8 conjugation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Fitting molecular fragments into electron density

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

The BACK domain in BTB-kelch proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

High-level expression and purification of recombinant SCF ubiquitin ligases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597819

Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex.

2 June 2018

1 reference

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https://api.crossref.org/works/10.1074%2FJBC.M112.437996

PhyloDraw: a phylogenetic tree drawing system

21 January 2018

1 reference

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https://pubmed.ncbi.nlm.nih.gov/23349464