(Q27676066)

2

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Aida Baharuddin

3

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David H Goetz

4

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Christopher J Farady

5

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Mick Ward

6

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Cheng-I Wang

7

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Charles S Craik

Journal of Molecular Biology

8

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language of work or name

English

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publication date

27 January 2012

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published in

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volume

415

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issue

4

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page(s)

699-715

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cites work

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Structural insight into distinct mechanisms of protease inhibition by antibodies

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Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase

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Structural basis for the inhibition of caspase-3 by XIAP

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Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

20 March 2017

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Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

20 March 2017

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The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex

20 March 2017

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Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase

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Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

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c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase

7 April 2017

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Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration

29 September 2017

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Tumor detection by imaging proteolytic activity

29 September 2017

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Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Prokaryotic expression of antibodies

29 September 2017

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Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Regulation of cellulase gene expression in the filamentous fungus Trichoderma reesei

29 September 2017

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Matrix metalloproteinases and the development of cancer

29 September 2017

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Length distribution of CDRH3 in antibodies

29 September 2017

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Production of recombinant proteins in the filamentous fungus Trichoderma reesei

29 September 2017

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The mechanism of inhibition of antibody-based inhibitors of membrane-type serine protease 1 (MT-SP1).

29 September 2017

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Changing views of the role of matrix metalloproteinases in metastasis

2 June 2018

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Relationships between inhibition constants and fractional inhibition in enzyme-catalyzed reactions with different numbers of reactants, different reaction mechanisms, and different types and mechanisms of inhibition.

2 June 2018

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The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli

2 June 2018

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17 The kinetics of reversible tight-binding inhibition

2 June 2018

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Improving the species cross-reactivity of an antibody using computational design

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268006

Expression of the serine protease matriptase and its inhibitor HAI-1 in epithelial ovarian cancer: correlation with clinical outcome and tumor clinicopathological parameters

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268006

Localization of epitopes for monoclonal antibodies to urokinase-type plasminogen activator: relationship between epitope localization and effects of antibodies on molecular interactions of the enzyme

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268006

Ecallantide for the treatment of acute attacks in hereditary angioedema

27 November 2018

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

The Reactive Site of Trypsin Inhibitors

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12 December 2020

Influence of cofactor binding and active site occupancy on the conformation of the macromolecular substrate exosite of factor VIIa

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Allosteric effects of a monoclonal antibody against thrombin exosite II

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10.1016/J.JMB.2011.11.036

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

22154938

1 reference