(Q27677455)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

title

Inhibiting alternative pathway complement activation by targeting the factor D exosite (English)

1 reference

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24 January 2020

0 references

3

1 reference

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24 January 2020

Christian Wiesmann

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

8

Daniel Kirchhofer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

author name string

Kenneth J Katschke

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Ping Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Robert F Kelley

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Mary A Mathieu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Philip E Hass

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Jeremy Murray

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

Menno van Lookeren Campagne

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

language of work or name

English

0 references

publication date

23 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

24 January 2020

published in

1 reference

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24 January 2020

volume

287

1 reference

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24 January 2020

issue

16

1 reference

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24 January 2020

page(s)

12886-12892

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family

24 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structures of C3b in complex with factors B and D give insight into complement convertase formation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Compstatin: a complement inhibitor on its way to clinical application

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structure of and influence of a tick complement inhibitor on human complement component 5

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structural insight into distinct mechanisms of protease inhibition by antibodies

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

The Structure of OMCI, a Novel Lipocalin Inhibitor of the Complement System

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structure of 3,4-dichloroisocoumarin-inhibited factor D

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structure of human factor D. A complement system protein at 2.0 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

REFMAC5 for the refinement of macromolecular crystal structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Inference of macromolecular assemblies from crystalline state

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Proteolytic activation of pro-macrophage-stimulating protein by hepsin.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Systemic complement activation in age-related macular degeneration

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Mechanism of action of factor D of the alternative complement pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Complement factor D in age-related macular degeneration

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Allosteric inhibition of complement function by a staphylococcal immune evasion protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Structural and mechanistic insight into how antibodies inhibit serine proteases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Genetic control of the alternative pathway of complement in humans and age-related macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Complement-targeted therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Human complement protein D catabolism by the rat kidney

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

The mechanism of inhibition of antibody-based inhibitors of membrane-type serine protease 1 (MT-SP1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339934

Novel anti-factor D monoclonal antibody inhibits complement and leukocyte activation in a baboon model of cardiopulmonary bypass

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.345082

Structure of diisopropyl fluorophosphate-inhibited factor D

21 January 2018

1 reference

12 December 2020

Anti-factor D monoclonal antibody, pulsatile flow and cardiotomy suction during cardiopulmonary bypass

1 reference

12 December 2020

Inhibition of complement, neutrophil, and platelet activation by an anti-factor D monoclonal antibody in simulated cardiopulmonary bypass circuits

1 reference

12 December 2020

Catalytic role of a surface loop of the complement serine protease factor D

1 reference

12 December 2020

Quantitation of complement factor D in human serum by a solid-phase radioimmunoassay

1 reference

12 December 2020

Renal filtration and catabolism of complement protein D

1 reference

12 December 2020

The anti-factor D antibody, MAb 166-32, inhibits the alternative pathway of the human complement system

1 reference

12 December 2020

The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.345082

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22362762%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

22362762

1 reference