(Q27684737)

2

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Hui Rong

3

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Zhifu Pan

4

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Yuka Inaba

5

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Lin Qiu

6

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Weili Zheng

7

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Shengchen Lin

8

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Rui Wang

9

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Zhao Wang

10

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Shanshan Wang

11

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Hongyan Liu

12

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Song Li

13

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Wen Xie

14

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Yong Li

Principles of activation and permeation in an anion-selective Cys-loop receptor

15

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language of work or name

English

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publication date

2013

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published in

Nature Communications

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volume

4

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page(s)

1937

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cites work

1 reference

Identification of a nuclear receptor for bile acids

21 April 2017

1 reference

Bile acids: natural ligands for an orphan nuclear receptor

21 April 2017

1 reference

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 April 2017

1 reference

The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice

21 April 2017

1 reference

Farnesoid X receptor is essential for normal glucose homeostasis

21 April 2017

1 reference

Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA

21 April 2017

1 reference

FXR agonist activity of conformationally constrained analogs of GW 4064

21 April 2017

1 reference

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

21 April 2017

1 reference

Structural basis for bile acid binding and activation of the nuclear receptor FXR

21 April 2017

1 reference

Regulation of carbohydrate metabolism by the farnesoid X receptor

21 April 2017

1 reference

Coot: model-building tools for molecular graphics

21 April 2017

1 reference

Revealing a steroid receptor ligand as a unique PPARγ agonist

21 April 2017

1 reference

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Ivermectin: A Potent New Antiparasitic Agent

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Impact of mass treatment of onchocerciasis with ivermectin on the transmission of infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

An amino acid substitution in the pore region of a glutamate-gated chloride channel enables the coupling of ligand binding to channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Ivermectin, an unconventional agonist of the glycine receptor chloride channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

A novel bile acid-activated vitamin D receptor signaling in human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Role of bile acids and bile acid receptors in metabolic regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

FXR: a metabolic regulator and cell protector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Efficacy and safety of a single-dose veterinary preparation of ivermectin versus 7-day high-dose albendazole for chronic strongyloidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

The farnesoid X receptor modulates hepatic carbohydrate metabolism during the fasting-refeeding transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Regulation of hepatic Insig-2 by the farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Recent advances and method development for drug target identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

Identification of a Drosophila melanogaster glutamate-gated chloride channel sensitive to the antiparasitic agent avermectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

7 January 2021

Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

7 January 2021

Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

7 January 2021

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS2924

7 January 2021