(Q27694791)

5

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author name string

Paul D Carr

1

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Cameron L Ewens

2

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Jin Dai

3

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David L Ollis

4

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Ian G Young

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells

7

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language of work or name

English

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publication date

1 November 2014

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published in

Biochemical Journal

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volume

463

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issue

3

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page(s)

393-403

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cites work

1 reference

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A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF

21 April 2017

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Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family

21 April 2017

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A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode

21 April 2017

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Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

21 April 2017

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The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

21 April 2017

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Protein crystallization by surface entropy reduction: optimization of the SER strategy

21 April 2017

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Phasercrystallographic software

21 April 2017

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Coot: model-building tools for molecular graphics

21 April 2017

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The Buccaneer software for automated model building. 1. Tracing protein chains

21 April 2017

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Refinement of macromolecular structures by the maximum-likelihood method

21 April 2017

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

21 April 2017

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Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL

21 April 2017

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SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibition

21 April 2017

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Murine interleukin-3: structure, dynamics, and conformational heterogeneity in solution

21 April 2017

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The RosettaDock server for local protein-protein docking

21 April 2017

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Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)

21 April 2017

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Human growth hormone and extracellular domain of its receptor: crystal structure of the complex

21 April 2017

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Efficiency of signalling through cytokine receptors depends critically on receptor orientation

21 April 2017

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Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

21 April 2017

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PHENIX: building new software for automated crystallographic structure determination

21 April 2017

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The role of dynamic conformational ensembles in biomolecular recognition

21 April 2017

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CRYSOL– a Program to Evaluate X-ray Solution Scattering of Biological Macromolecules from Atomic Coordinates

21 April 2017

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Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils

21 April 2017

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Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia.

21 January 2018

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Elevated expression of IL-3Ralpha in acute myelogenous leukemia is associated with enhanced blast proliferation, increased cellularity, and poor prognosis.

21 January 2018

1 reference

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Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells

21 January 2018

1 reference

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IL-3, IL-5, and GM-CSF signaling: crystal structure of the human beta-common receptor

21 January 2018

1 reference

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Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor

21 January 2018

1 reference

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Interleukin-3 binding to the murine betaIL-3 and human betac receptors involves functional epitopes formed by domains 1 and 4 of different protein chains

21 January 2018

1 reference

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The molecular regulation of Janus kinase (JAK) activation

21 January 2018

1 reference

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Two modes of beta-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3.

21 January 2018

1 reference

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An improved resolution structure of the human beta common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope

21 January 2018

1 reference

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Expression, crystallization and derivatization of the complete extracellular domain of the beta(c) subunit of the human IL-5, IL-3 and GM-CSF receptors

21 January 2018

1 reference

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Improved low-resolution crystallographic refinement with Phenix and Rosetta

21 January 2018

1 reference

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Stereochemistry of polypeptide chain configurations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140863

Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140863

Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law.

21 January 2018

1 reference

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DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

21 January 2018

1 reference

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A convenient method for preparation of an engineered mouse interleukin-3 analog with high solubility and wild-type bioactivity.

21 January 2018

1 reference

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Exchange enhanced sensitivity gain for solvent-exchangeable protons in 2D 1H-15N heteronuclear correlation spectra acquired with band-selective pulses

21 January 2018

1 reference

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1H, 13C and 15N resonance assignments of a highly-soluble murine interleukin-3 analogue with wild-type bioactivity

21 January 2018

1 reference

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A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20140863

Structural design and molecular evolution of a cytokine receptor superfamily

21 January 2018

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PRIMUS: a Windows PC-based system for small-angle scattering data analysis

21 January 2018

1 reference

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