(Q27727737)

12

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Henning Urlaub

9

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Berthold Kastner

10

object named as

Berthold Kastner

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author name string

Reinhard Rauhut

1

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Patrizia Fabrizio

2

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Olexandr Dybkov

3

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Klaus Hartmuth

4

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Vladimir Pena

5

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Ashwin Chari

6

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Vinay Kumar

7

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Chung-Tien Lee

8

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Holger Stark

The spliceosome: design principles of a dynamic RNP machine

11

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language of work or name

English

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publication date

23 September 2016

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published in

Science

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volume

353

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issue

6306

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page(s)

1399-1405

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cites work

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosome

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Prp2-mediated protein rearrangements at the catalytic core of the spliceosome as revealed by dcFCCS.

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Spliceosome activation by PRP2 ATPase prior to the first transesterification reaction of pre-mRNA splicing

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Mechanical devices of the spliceosome: motors, clocks, springs, and things

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Structure of a yeast spliceosome at 3.6-angstrom resolution

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Prp8 protein: at the heart of the spliceosome

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

The 3.8 Å structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Molecular architecture of the human U4/U6.U5 tri-snRNP

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Crystal Structure of a Self-Spliced Group II Intron

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

A general two-metal-ion mechanism for catalytic RNA

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Crystal structure of a group II intron in the pre-catalytic state

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Visualizing Group II Intron Catalysis through the Stages of Splicing

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Crystal structure of the human eIF4AIII-CWC22 complex shows how a DEAD-box protein is inhibited by a MIF4G domain

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

The DExD/H-box ATPase Prp2p destabilizes and proofreads the catalytic RNA core of the spliceosome

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

An Unusual Hydrophobic Core Confers Extreme Flexibility to HEAT Repeat Proteins

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Structure of a yeast activated spliceosome at 3.5 Å resolution

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

A new generation of the IMAGIC image processing system

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Accurate determination of local defocus and specimen tilt in electron microscopy

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

UCSF Chimera--a visualization system for exploratory research and analysis

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Features and development of Coot

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Structure and assembly of the SF3a splicing factor complex of U2 snRNP

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Identification and characterization of Prp45p and Prp46p, essential pre-mRNA splicing factors

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Structure of the yeast Pml1 splicing factor and its integration into the RES complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Crystal structure of the Pml1p subunit of the yeast precursor mRNA retention and splicing complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

Prp43p contains a processive helicase structural architecture with a specific regulatory domain

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAG1906

RELION: implementation of a Bayesian approach to cryo-EM structure determination

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAG1906