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The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells
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instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
22302096
retrieved
13 November 2016
title
The aurora kinase A inhibitor MLN8237 enhances cisplatin-induced cell death in esophageal adenocarcinoma cells
(English)
1 reference
stated in
PubMed
PubMed ID
22302096
retrieved
13 November 2016
main subject
adenocarcinoma
1 reference
based on heuristic
inferred from title
cisplatin
1 reference
based on heuristic
inferred from title
cell death
1 reference
based on heuristic
inferred from title
author
Regine Schneider-Stock
series ordinal
9
object named as
Regine Schneider-Stock
0 references
author name string
Vikas Sehdev
series ordinal
1
0 references
DunFa Peng
series ordinal
2
0 references
Mohammed Soutto
series ordinal
3
0 references
M Kay Washington
series ordinal
4
0 references
Frank Revetta
series ordinal
5
0 references
Jeffrey Ecsedy
series ordinal
6
0 references
Alexander Zaika
series ordinal
7
0 references
Tilman T Rau
series ordinal
8
0 references
Regine Schneider-Stock
series ordinal
9
0 references
Abbes Belkhiri
series ordinal
10
0 references
Wael El-Rifai
series ordinal
11
0 references
language of work or name
English
0 references
publication date
March 2012
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published in
Molecular Cancer Therapeutics
1 reference
stated in
PubMed
volume
11
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issue
3
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page(s)
763-74
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describes a project that uses
ImageJ
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3297687/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
20 March 2017
Surfing the p53 network
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
7 April 2017
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
20 March 2017
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
1 reference
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PubMed Central
reference URL
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20 March 2017
The Ki-67 protein: from the known and the unknown
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PubMed Central
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20 March 2017
Assignment of STK6 to human chromosome 20q13.2-->q13.3 and a pseudogene STK6P to 1q41-->q42
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PubMed Central
reference URL
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20 March 2017
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis
1 reference
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PubMed Central
reference URL
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retrieved
20 March 2017
Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Loss of TFF1 is associated with activation of NF-κB-mediated inflammation and gastric neoplasia in mice and humans
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Aurora inhibitor MLN8237 in combination with docetaxel enhances apoptosis and anti-tumor activity in mantle cell lymphoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Dopamine and cAMP regulated phosphoprotein MW 32 kDa is overexpressed in early stages of gastric tumorigenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Aurora kinase inhibitors--rising stars in cancer therapeutics?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Initial testing of the aurora kinase A inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Aurora-A interacts with Cyclin B1 and enhances its stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Frequent overexpression of Aurora Kinase A in upper gastrointestinal adenocarcinomas correlates with potent antiapoptotic functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
The multidisciplinary management of gastrointestinal cancer. Multimodal treatment of oesophageal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: is acute apoptosis an "off-target" effect?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Palliative chemotherapy for recurrent and metastatic esophageal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Amplification and overexpression of Aurora-A in esophageal squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Molecular mechanisms of pancreatic carcinogenesis.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Biologic and clinical variations of adenocarcinoma at the esophago-gastric junction: relevance of a topographic-anatomic subclassification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
The common and distinct target genes of the p53 family transcription factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Cisplatin and platinum drugs at the molecular level. (Review)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Secular trends in the epidemiology and outcome of Barrett's oesophagus in Olmsted County, Minnesota
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Molecular biology of esophageal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
29 September 2017
Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
2 June 2018
Epidermal growth factor receptor (EGFR) is overexpressed in high-grade dysplasia and adenocarcinoma of the esophagus and may represent a biomarker of histological progression in Barrett's esophagus (BE).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
Copy number increase of aurora kinase A in colorectal cancers: a correlation with tumor progression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
Aurora kinase A in Barrett's carcinogenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
Time trends incidence of both major histologic types of esophageal carcinomas in selected countries, 1973-1995
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
P53 mutational status improves estimation of prognosis in patients with curatively resected adenocarcinoma in Barrett's esophagus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
Changing patterns in the incidence of esophageal and gastric carcinoma in the United States
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
TP53 gene mutations and p53 protein immunoreactivity in malignant and premalignant Barrett's esophagus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3297687
retrieved
27 November 2018
Promoter specificity and stability control of the p53-related protein p73
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
High rate of lymph-node metastasis in submucosal esophageal squamous-cell carcinomas and adenocarcinomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Gains and Amplifications of c-myc, EGFR, and 20.q13 Loci in the No Dysplasia-Dysplasia-Adenocarcinoma Sequence of Barrett's Esophagus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Immunohistochemical evaluation of a panel of tumor cell markers during malignant progression in Barrett esophagus
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Rising incidence of adenocarcinoma of the esophagus and gastric cardia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Mitotic kinase expression and colorectal cancer progression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Genome-wide analysis of genetic alterations in Barrett's adenocarcinoma using single nucleotide polymorphism arrays
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22302096
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1535-7163.MCT-11-0623
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4701860
OpenCitations bibliographic resource ID
4701860
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4701860
PMCID
3297687
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4701860
PubMed ID
22302096
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4701860
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