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Therapeutic targeting of cancers with loss of PTEN function
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scholarly article
1 reference
stated in
PubMed
PubMed ID
24387334
retrieved
13 November 2016
title
Therapeutic targeting of cancers with loss of PTEN function
(English)
1 reference
stated in
PubMed
PubMed ID
24387334
retrieved
13 November 2016
author name string
Lloye M Dillon
series ordinal
1
0 references
Todd W Miller
series ordinal
2
0 references
publication date
January 2014
0 references
published in
Current Drug Targets
0 references
volume
15
0 references
page(s)
65-79
0 references
issue
1
0 references
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29 September 2017
Recurrent R-spondin fusions in colon cancer
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29 September 2017
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240.
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29 September 2017
Sequence analysis of mutations and translocations across breast cancer subtypes
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29 September 2017
Cancer network disruption by a single molecule inhibitor targeting both histone deacetylase activity and phosphatidylinositol 3-kinase signaling
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29 September 2017
Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas
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29 September 2017
Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent
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29 September 2017
PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors
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29 September 2017
Functional analysis of the protein phosphatase activity of PTEN
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29 September 2017
PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity
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29 September 2017
Lifetime cancer risks in individuals with germline PTEN mutations.
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29 September 2017
Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors
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29 September 2017
Pathologic scoring of PTEN immunohistochemistry in endometrial carcinoma is highly reproducible
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29 September 2017
Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer
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29 September 2017
Discovery of new aminopyrimidine-based phosphoinositide 3-kinase beta (PI3Kβ) inhibitors with selectivity over PI3Kα.
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29 September 2017
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability
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29 September 2017
Novel phosphoinositide 3-kinase/mTOR dual inhibitor, NVP-BGT226, displays potent growth-inhibitory activity against human head and neck cancer cells in vitro and in vivo
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29 September 2017
Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy.
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29 September 2017
Burden of disease and unmet needs in tuberous sclerosis complex with neurological manifestations: systematic review
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29 September 2017
Evaluation of the association of PIK3CA mutations and PTEN loss with efficacy of trastuzumab therapy in metastatic breast cancer.
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29 September 2017
α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells
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29 September 2017
PTEN loss in the continuum of common cancers, rare syndromes and mouse models.
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29 September 2017
Antitumor efficacy of PKI-587, a highly potent dual PI3K/mTOR kinase inhibitor
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29 September 2017
Everolimus for advanced pancreatic neuroendocrine tumors.
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29 September 2017
Non-genomic loss of PTEN function in cancer: not in my genes.
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29 September 2017
PTEN restoration and PIK3CB knockdown synergistically suppress glioblastoma growth in vitro and in xenografts
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells
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29 September 2017
Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers
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29 September 2017
Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis
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29 September 2017
PTEN deficiency in endometrioid endometrial adenocarcinomas predicts sensitivity to PARP inhibitors
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29 September 2017
Iniparib, a PARP1 inhibitor for the potential treatment of cancer, including triple-negative breast cancer
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29 September 2017
Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
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29 September 2017
MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells.
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29 September 2017
Phosphoinositide 3-kinase pathway activation in phosphate and tensin homolog (PTEN)-deficient prostate cancer cells is independent of receptor tyrosine kinases and mediated by the p110beta and p110delta catalytic subunits
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor
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29 September 2017
Isoform-specific phosphoinositide 3-kinase inhibitors exert distinct effects in solid tumors
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29 September 2017
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
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29 September 2017
The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Reverse-phase protein microarrays for theranostics and patient tailored therapy
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29 September 2017
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016.
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29 September 2017
PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability
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29 September 2017
PTEN: a new guardian of the genome.
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29 September 2017
Genetic and phenotypic heterogeneity in the PTEN hamartoma tumour syndrome.
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29 September 2017
Potential value of PTEN in predicting cetuximab response in colorectal cancer: an exploratory study
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29 September 2017
An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Txnip balances metabolic and growth signaling via PTEN disulfide reduction
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
The nuclear affairs of PTEN.
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29 September 2017
A vascular targeted pan phosphoinositide 3-kinase inhibitor prodrug, SF1126, with antitumor and antiangiogenic activity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
The selective poly(ADP-ribose) polymerase-1(2) inhibitor, CEP-8983, increases the sensitivity of chemoresistant tumor cells to temozolomide and irinotecan but does not potentiate myelotoxicity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Differential redox regulation within the PTP superfamily
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Mitogen-activated protein kinase kinase-4 promotes cell survival by decreasing PTEN expression through an NF kappa B-dependent pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Mutation-positive and mutation-negative patients with Cowden and Bannayan-Riley-Ruvalcaba syndromes associated with distinct 10q haplotypes
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29 September 2017
The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
c-Jun promotes cellular survival by suppression of PTEN.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
Increased PTEN expression due to transcriptional activation of PPARgamma by Lovastatin and Rosiglitazone
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29 September 2017
DJ-1, a novel regulator of the tumor suppressor PTEN.
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29 September 2017
Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.
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29 September 2017
CCI-779 Wyeth
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29 September 2017
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PTEN: The down side of PI 3-kinase signalling.
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29 September 2017
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
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29 September 2017
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model
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29 September 2017
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN.
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29 September 2017
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
29 September 2017
Assessing the order of critical alterations in prostate cancer development and progression by IHC: further evidence that PTEN loss occurs subsequent to ERG gene fusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
NLK is a novel therapeutic target for PTEN deficient tumour cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
Phosphatase and tensin homolog expression related to cetuximab effects in colorectal cancer patients: a meta-analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
Phase I safety, pharmacokinetic, and pharmacodynamic study of the oral phosphatidylinositol-3-kinase and mTOR inhibitor BGT226 in patients with advanced solid tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
Regulation of PTEN activity by its carboxyl-terminal autoinhibitory domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
2 June 2018
A novel selective small-molecule PI3K inhibitor is effective against human multiple myeloma in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
When overgrowth bumps into cancer: the PTEN-opathies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: the discovery of AZD8055 and AZD2014.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
PTEN losses exhibit heterogeneity in multifocal prostatic adenocarcinoma and are associated with higher Gleason grade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
The tumor suppressor PTEN is exported in exosomes and has phosphatase activity in recipient cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Sirolimus therapy for fibromatosis and multifocal renal cell carcinoma in a child with tuberous sclerosis complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
PTEN status in advanced colorectal cancer treated with cetuximab.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Mechanistic insights into maintenance of high p53 acetylation by PTEN.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
PTEN Autoregulates Its Expression by Stabilization of p53 in a Phosphatase-Independent Manner
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
Promoter methylation and silencing of PTEN in gastric carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4310752
retrieved
27 November 2018
PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Epigenetic and genetic alterations of PTEN in hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PTEN promoter is methylated in a proportion of invasive breast cancers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Treatment with olaparib in a patient with PTEN-deficient endometrioid endometrial cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Epigenetic silencing of the PTEN gene in melanoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pilot Study of the Mechanism of Action of Preoperative Trastuzumab in Patients with Primary Operable Breast Tumors Overexpressing HER2
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24387334
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2174/1389450114666140106100909
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
782506
OpenCitations bibliographic resource ID
782506
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
782506
PMCID
4310752
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
782506
PubMed ID
24387334
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
782506
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