(Q38320448)

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Acetylated Sp1 inhibits PTEN expression through binding to PTEN core promoter and recruitment of HDAC1 and promotes cancer cell migration and invasion

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Europe PubMed Central

PubMed publication ID

2 September 2017

Acetylated Sp1 inhibits PTEN expression through binding to PTEN core promoter and recruitment of HDAC1 and promotes cancer cell migration and invasion (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

author name string

Xiao-Xing Kou

1

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Europe PubMed Central

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2 September 2017

Ting Hao

2

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Europe PubMed Central

PubMed publication ID

2 September 2017

Zhen Meng

3

1 reference

Europe PubMed Central

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2 September 2017

Yan-Heng Zhou

4

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2 September 2017

Ye-Hua Gan

5

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2 September 2017

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publication date

26 October 2012

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Europe PubMed Central

PubMed publication ID

2 September 2017

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Europe PubMed Central

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2 September 2017

34

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Europe PubMed Central

PubMed publication ID

2 September 2017

1

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Europe PubMed Central

PubMed publication ID

2 September 2017

58-67

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Europe PubMed Central

PubMed publication ID

2 September 2017

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1 reference

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Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs

1 reference

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21 January 2018

Sp1: emerging roles--beyond constitutive activation of TATA-less housekeeping genes

1 reference

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Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?

1 reference

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Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance.

1 reference

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21 January 2018

Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcome

1 reference

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21 January 2018

Targeting Sp1 transcription factors in prostate cancer therapy.

1 reference

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21 January 2018

Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Trichostatin A induces transforming growth factor beta type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1.NF-Y complex

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

The histone deacetylase inhibitor trichostatin A mediates upregulation of 5-lipoxygenase promoter activity by recruitment of Sp1 to distinct GC-boxes

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Histone deacetylase 1 can repress transcription by binding to Sp1.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Sp1 and Sp3 recruit histone deacetylase to repress transcription of human telomerase reverse transcriptase (hTERT) promoter in normal human somatic cells

1 reference

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21 January 2018

Silencing of transcription of the human luteinizing hormone receptor gene by histone deacetylase-mSin3A complex

1 reference

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21 January 2018

Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase

1 reference

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21 January 2018

Correlation between arthroscopic diagnosis of osteoarthritis and synovitis of the human temporomandibular joint and keratan sulfate levels in the synovial fluid

1 reference

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21 January 2018

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1 reference

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21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Suppression of PTEN expression by NF-kappa B prevents apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Pten dose dictates cancer progression in the prostate

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

CBF-1 (RBP-J kappa) binds to the PTEN promoter and regulates PTEN gene expression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

c-Jun promotes cellular survival by suppression of PTEN.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Regulation of PTEN transcription by p53

1 reference

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21 January 2018

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

The AP-2alpha transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene

1 reference

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21 January 2018

PPARgamma activator rosiglitazone inhibits cell migration via upregulation of PTEN in human hepatocarcinoma cell line BEL-7404.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Epiregulin promotes migration and invasion of salivary adenoid cystic carcinoma cell line SACC-83 through activation of ERK and Akt.

1 reference

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21 January 2018

Role for histone deacetylase 1 in human tumor cell proliferation

1 reference

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21 January 2018

PTEN/AKT pathway involved in histone deacetylases inhibitor induced cell growth inhibition and apoptosis of oral squamous cell carcinoma cells

1 reference

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21 January 2018

Functional interactions between the retinoblastoma (Rb) protein and Sp-family members: superactivation by Rb requires amino acids necessary for growth suppression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

The RNA polymerase II core promoter: a key component in the regulation of gene expression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Sp1 inhibits proliferation and induces apoptosis in vascular smooth muscle cells by repressing p21WAF1/Cip1 transcription and cyclin D1-Cdk4-p21WAF1/Cip1 complex formation.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

The D-domain of Sp3 modulates its protein levels and activation of the p21(CIP1/WAF1) promoter

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS336

21 January 2018

Akt activation is responsible for enhanced migratory and invasive behavior of arsenic-transformed human bronchial epithelial cells

1 reference

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21 January 2018

Identifiers

10.1093/CARCIN/BGS336

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 September 2017

ResearchGate publication ID

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