(Q39545547)

12 September 2017

α-Mannosidase 2C1 attenuates PTEN function in prostate cancer cells (English)

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12 September 2017

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Lizhi He

1

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12 September 2017

Catherine Fan

2

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12 September 2017

Anil Kapoor

3

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12 September 2017

Alistair J Ingram

4

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12 September 2017

Adrian P Rybak

5

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12 September 2017

Richard C Austin

6

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12 September 2017

Jeffery Dickhout

7

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12 September 2017

Jean-Claude Cutz

8

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12 September 2017

James Scholey

9

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12 September 2017

Damu Tang

10

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12 September 2017

language of work or name

English

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publication date

1 January 2011

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12 September 2017

Nature Communications

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12 September 2017

2

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12 September 2017

307

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https://scigraph.springernature.com/pub.10.1038/ncomms1309

12 September 2017

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cites work

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

PI3K pathway alterations in cancer: variations on a theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Downregulation of PTEN/MMAC/TEP1 expression in human prostate cancer cell line DU145 by growth stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The multiple roles of PTEN in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Molecular genetics of prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Genetic background controls tumor development in PTEN-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Pten inactivation and the emergence of androgen-independent prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Co-existence of high levels of the PTEN protein with enhanced Akt activation in renal cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Shank-interacting protein-like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Cloning, expression and characterization of a cDNA (6A8) encoding a novel human alpha-mannosidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The importance of trimming reactions on asparagine-linked oligosaccharides for protein quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Long-term expression of a transferred gene in Epstein-Barr virus transformed human B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Suppression of 6A8 alpha-mannosidase gene expression reduced the potentiality of growth and metastasis of human nasopharyngeal carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Transforming growth factor-beta promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

CIP2A inhibits PP2A in human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The retention signal for soluble proteins of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

DJ-1, a novel regulator of the tumor suppressor PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Endogenous tumor suppression mediated by PTEN involves survivin gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

hMan2c1 transgene promotes tumor progress in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Alterations in glycosylation as biomarkers for cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

Akt is activated in response to an apoptotic signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS1309

A human prostatic epithelial model of hormonal carcinogenesis

21 January 2018

1 reference

12 December 2020

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

1 reference

12 December 2020

A third-generation lentivirus vector with a conditional packaging system

2 references

12 December 2020

https://api.crossref.org/works/10.1038%2FNCOMMS1309

7 January 2021

inferred from DOI database lookup

Cowden syndrome (multiple hamartoma syndrome).

1 reference

12 December 2020

Prediction of prostate-specific antigen recurrence in men with long-term follow-up postprostatectomy using quantitative nuclear morphometry

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS1309

1 reference

Dimensions Publication ID

12 September 2017

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0 references

1 reference