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IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma
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scholarly article
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PubMed
PubMed ID
26268241
retrieved
13 November 2016
title
IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma
(English)
1 reference
stated in
PubMed
PubMed ID
26268241
retrieved
13 November 2016
main subject
cell biology
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patient
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angioimmunoblastic T-cell lymphoma
1 reference
based on heuristic
inferred from title
author
German Ott
series ordinal
21
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Andreas Rosenwald
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6
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Louis M Staudt
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23
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Qiang Gong
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Qiang Gong
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3
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Dennis D Weisenburger
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18
object named as
Dennis D Weisenburger
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Randy D Gascoyne
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7
object named as
Randy D Gascoyne
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Wing C Chan
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26
object named as
Wing C Chan
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Julie M Vose
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24
object named as
Julie Vose
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Timothy W McKeithan
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2
object named as
Timothy W McKeithan
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Javeed Iqbal
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25
object named as
Javeed Iqbal
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Timothy Greiner
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19
object named as
Timothy C Greiner
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Joseph M Rohr
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12
object named as
Joseph Rohr
0 references
Christian Steidl
series ordinal
14
object named as
Christian Steidl
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Alyssa Bouska
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5
object named as
Alyssa Bouska
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Stacy S Hung
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17
object named as
Stacy Hung
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Eleanor G Rogan
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22
object named as
Eleanor G Rogan
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author name string
Chao Wang
series ordinal
1
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Weiwei Zhang
series ordinal
4
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Xiwei Wu
series ordinal
8
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Jinhui Wang
series ordinal
9
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Zahid Muhammad
series ordinal
10
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Bei Jiang
series ordinal
11
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Andrew Cannon
series ordinal
13
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Kai Fu
series ordinal
15
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Yuping Li
series ordinal
16
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Lynette Smith
series ordinal
20
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language of work or name
English
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publication date
8 October 2015
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published in
Blood
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volume
126
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issue
15
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page(s)
1741-52
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cites work
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma
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The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
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The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate
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The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells
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TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
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IDH mutation impairs histone demethylation and results in a block to cell differentiation
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Global transcriptome analysis and enhancer landscape of human primary T follicular helper and T effector lymphocytes.
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TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients
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Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma
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A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma
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A targeted mutational landscape of angioimmunoblastic T-cell lymphoma.
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Induction of sarcomas by mutant IDH2
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29 September 2017
The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.
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29 September 2017
IDH mutations in acute myeloid leukemia
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Clinicopathologic characteristics of angioimmunoblastic T-cell lymphoma: analysis of the international peripheral T-cell lymphoma project
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The aggressive peripheral T-cell lymphomas: 2012 update on diagnosis, risk stratification, and management
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29 September 2017
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.
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29 September 2017
A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples
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IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study
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Advances in the understanding and management of angioimmunoblastic T-cell lymphoma
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29 September 2017
Gene expression profiling in lymphoma diagnosis and management
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29 September 2017
Paraffin-based 6-gene model predicts outcome in diffuse large B-cell lymphoma patients treated with R-CHOP.
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29 September 2017
Vascular endothelial growth factor-A is expressed both on lymphoma cells and endothelial cells in angioimmunoblastic T-cell lymphoma and related to lymphoma progression.
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29 September 2017
Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.
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2 June 2018
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
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2 June 2018
Human dendritic cells induce the differentiation of interleukin-21-producing T follicular helper-like cells through interleukin-12.
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2 June 2018
Angioimmunoblastic T-cell lymphoma: a neoplasm of germinal-center T-helper cells?
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2 June 2018
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells
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27 November 2018
Efficacy of 5-Azacytidine in aTET2mutated angioimmunoblastic T cell lymphoma
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27 November 2018
IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication
1 reference
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27 November 2018
Early commitment of naïve human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12.
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27 November 2018
Gene expression analysis of angioimmunoblastic lymphoma indicates derivation from T follicular helper cells and vascular endothelial growth factor deregulation
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27 November 2018
TET2 and DNMT3A mutations in human T-cell lymphoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26268241
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The fundamental role of epigenetic events in cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26268241
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1182/BLOOD-2015-05-644591
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2363173
OpenCitations bibliographic resource ID
2363173
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2363173
PMC publication ID
4600014
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2363173
PubMed ID
26268241
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2363173
ResearchGate publication ID
280979927
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