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The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae
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scholarly article
1 reference
stated in
PubMed
PubMed ID
19733178
retrieved
1 December 2016
title
The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae
(English)
1 reference
stated in
PubMed
PubMed ID
19733178
retrieved
1 December 2016
main subject
Saccharomyces cerevisiae
0 references
MRNA-binding protein NPL3 YDR432W
1 reference
stated in
GOA release 2020-03-11
author name string
Miles F Wilkinson
series ordinal
2
0 references
Carlos I González
series ordinal
3
0 references
language of work or name
English
0 references
publication date
4 December 2009
0 references
published in
Journal of Molecular Biology
1 reference
stated in
PubMed
PubMed ID
19733178
retrieved
1 December 2016
volume
394
0 references
page(s)
410-22
0 references
cites work
A single SR-like protein, Npl3, promotes pre-mRNA splicing in budding yeast
1 reference
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PubMed Central
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20 March 2017
Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation
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PubMed Central
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20 March 2017
Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay
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PubMed Central
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20 March 2017
A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export
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PubMed Central
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20 March 2017
Structure of the Yeast SR Protein Npl3 and Interaction with mRNA 3′-End Processing Signals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI.
1 reference
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PubMed Central
reference URL
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20 March 2017
Nuclear export of ribosomal 60S subunits by the general mRNA export receptor Mex67-Mtr2.
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PubMed Central
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20 March 2017
The DEAD-box RNA helicase Dbp5 functions in translation termination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Inositol hexakisphosphate and Gle1 activate the DEAD-box protein Dbp5 for nuclear mRNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Nuclear export of hnRNP Hrp1p and nuclear export of hnRNP Npl3p are linked and influenced by the methylation state of Npl3p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
U2AF homology motifs: protein recognition in the RRM world
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Splicing enhances translation in mammalian cells: an additional function of the exon junction complex
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
The Mtr2-Mex67 NTF2-like domain complex. Structural insights into a dual role of Mtr2 for yeast nuclear export
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Nuclear import of Upf3p is mediated by importin-alpha/-beta and export to the cytoplasm is required for a functional nonsense-mediated mRNA decay pathway in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Functional interaction between Ssu72 and the Rpb2 subunit of RNA polymerase II in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Conserved SR protein kinase functions in nuclear import and its action is counteracted by arginine methylation in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Arginine methylation facilitates the nuclear export of hnRNP proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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20 March 2017
Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Roles of ABF1, NPL3, and YCL54 in silencing in Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
The majority of yeast UPF1 co-localizes with polyribosomes in the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 March 2017
Pre-mRNA processing reaches back to transcription and ahead to translation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
7 April 2017
High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
7 April 2017
The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
7 April 2017
Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
7 April 2017
Getting started with yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
7 April 2017
Roles of the TREX complex in nuclear export of mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Ratcheting mRNA out of the nucleus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Transport of messenger RNA from the nucleus to the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Arginine methylation of yeast mRNA-binding protein Npl3 directly affects its function, nuclear export, and intranuclear protein interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Cotranscriptional mRNP assembly: from the DNA to the nuclear pore
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Nonsense-mediated mRNA decay in mammals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Yeast shuttling SR proteins Npl3p, Gbp2p, and Hrb1p are part of the translating mRNPs, and Npl3p can function as a translational repressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
GTP hydrolysis by eRF3 facilitates stop codon decoding during eukaryotic translation termination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Poly(A)-binding protein acts in translation termination via eukaryotic release factor 3 interaction and does not influence [PSI(+)] propagation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Nonsense-mediated mRNA decay in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Eukaryotic translation initiation: there are (at least) two sides to every story
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Upf1p, Nmd2p, and Upf3p are interacting components of the yeast nonsense-mediated mRNA decay pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Synthetic enhancement in gene interaction: a genetic tool come of age.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Nonsense mutations in the can1 locus of Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Gene products that promote mRNA turnover in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
29 September 2017
Nonsense codons trigger an RNA partitioning shift
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
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2 June 2018
Dual luciferase assay system for rapid assessment of gene expression in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
2 June 2018
Making sense of nonsense in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
2 June 2018
Purification and characterization of the Upf1 protein: a factor involved in translation and mRNA degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
2 June 2018
Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
20 June 2018
Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
27 November 2018
The spanish connection: transcription and mRNA processing get even closer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
27 November 2018
Linking mRNA turnover and translation: assessing the polyribosomal association of mRNA decay factors and degradative intermediates.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2783964
retrieved
27 November 2018
Unravelling mRNA export
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19733178
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Gle1 does double duty
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19733178
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19733178
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
7The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19733178
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19733178
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19733178
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JMB.2009.08.067
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release_y7lm5vdnvvc4lmimv5i5uaaqrm
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Fatcat
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https://api.fatcat.wiki/v0/release/y7lm5vdnvvc4lmimv5i5uaaqrm
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24 November 2022
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mapped directly with Wikidata item
PMCID
2783964
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PubMed ID
19733178
1 reference
stated in
PubMed
PubMed ID
19733178
retrieved
1 December 2016
ResearchGate publication ID
26792249
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