(Q27936406)

English

Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation

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PubMed publication ID

1 December 2016

Genome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation (English)

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PubMed publication ID

1 December 2016

Saccharomyces cerevisiae

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based on heuristic

inferred from title

6

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7

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2

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Shawn Hoon

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author name string

Paola Fabrizio

1

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Mehrnaz Shamalnasab

3

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Abdulaye Galbani

4

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Min Wei

5

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Valter D Longo

8

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language of work or name

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publication date

15 July 2010

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PubMed publication ID

1 December 2016

6

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7

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e1001024

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copyright license

Creative Commons Attribution 4.0 International

15 July 2010

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April 2022 Public Data File from Crossref

copyright status

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Sch9 is a major target of TORC1 in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Yeast AMID homologue Ndi1p displays respiration-restricted apoptotic activity and is involved in chronological aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Extension of chronological life span in yeast by decreased TOR pathway signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Sir2 blocks extreme life-span extension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Evolution of the acyl-CoA binding protein (ACBP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

An AIF orthologue regulates apoptosis in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Novel methyltransferase for modified uridine residues at the wobble position of tRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Global analysis of protein expression in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Statistical significance for genomewide studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Functional profiling of the Saccharomyces cerevisiae genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Depletion of acyl-coenzyme A-binding protein affects sphingolipid synthesis and causes vesicle accumulation and membrane defects in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Regulation of longevity and stress resistance by Sch9 in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Nuclear export of S6K1 II is regulated by protein kinase CK2 phosphorylation at Ser-17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Significance analysis of time course microarray experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

20 March 2017

Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

The chemical genomic portrait of yeast: uncovering a phenotype for all genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

Cellular senescence: when bad things happen to good cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

GO::TermFinder--open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

Genetics: influence of TOR kinase on lifespan in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

Autophagy genes are essential for dauer development and life-span extension in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

7 April 2017

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Protein homeostasis and aging: The importance of exquisite quality control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Disruption of protein kinase A in mice enhances healthy aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

A molecular mechanism of chronological aging in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Autophagy genes and ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Yeast chemical genomics and drug discovery: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Construction, verification and experimental use of two epitope-tagged collections of budding yeast strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

An integrated platform of genomic assays reveals small-molecule bioactivities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Aging and survival: the genetics of life span extension by dietary restriction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Ageing and the regulation of protein synthesis: a balancing act?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Lifespan and reproduction in Drosophila: New insights from nutritional geometry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Characterization of differentiated quiescent and nonquiescent cells in yeast stationary-phase cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

DNA replication stress is a determinant of chronological lifespan in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

A concentric circle model of multivesicular body cargo sorting.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Transcriptional regulation of phospholipid biosynthesis is linked to fatty acid metabolism by an acyl-CoA-binding-protein-dependent mechanism in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Isolation of quiescent and nonquiescent cells from yeast stationary-phase cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Ras: the other pro-aging pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Superoxide is a mediator of an altruistic aging program in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Life span of individual yeast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

The chronological life span of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Evolutionary medicine: from dwarf model systems to healthy centenarians?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

SOD2 functions downstream of Sch9 to extend longevity in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

A conserved regulatory system for aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Stationary phase in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Daughter cells of Saccharomyces cerevisiae from old mothers display a reduced life span

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

29 September 2017

Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

2 June 2018

EDGE: extraction and analysis of differential gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2904796

2 June 2018

Genome-wide analysis of barcoded Saccharomyces cerevisiae gene-deletion mutants in pooled cultures.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae: common targets and prevention by calorie restriction

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

Regulation of longevity and stress resistance: a molecular strategy conserved from yeast to humans?

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

A global view of CK2 function and regulation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

Yeast holoenzyme of protein kinase CK2 requires both beta and beta' regulatory subunits for its activity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

TBBz but not TBBt discriminates between two molecular forms of CK2 in vivo and its implications.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

Nutritional control of aging

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

A direct approach to false discovery rates

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1001024

21 January 2018

An intervention resembling caloric restriction prolongs life span and retards aging in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 5 adenylyl cyclase disruption increases longevity and protects against stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The chronological life span of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein oxidation and aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/20657825

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1001024

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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