(Q27938355)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

AAA family ATPase CDC6 YJL194W

23 February 2020

main subject

1 reference

GOA release 2020-03-11

author

Alejandra Fernández-Cid

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Christian Speck

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Cecile Evrin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Juergen Zech

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

M Carmen Herrera

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Alberto Riera

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Pippa Clarke

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Shlomo Brill

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Rudi Lurz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

1 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

number of pages

11

1 reference

inferred from page(s)

published in

Nucleic Acids Research

2 references

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

3162-3172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

23 February 2020

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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20 March 2017

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A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing

20 March 2017

1 reference

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I-TASSER server for protein 3D structure prediction

20 March 2017

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Replication origin recognition and deformation by a heterodimeric archaeal Orc1 complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Structure and function of Cdc6/Cdc18: implications for origin recognition and checkpoint control

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

DaliLite workbench for protein structure comparison

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Cdc6 protein causes premature entry into S phase in a mammalian cell-free system

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

A human protein related to yeast Cdc6p

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

The structural basis for MCM2-7 helicase activation by GINS and Cdc45.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

The Cdc6 nucleotide-binding site regulates its activity in DNA replication in human cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Multiple Cdt1 molecules act at each origin to load replication-competent Mcm2-7 helicases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Structure and function of the AAA+ nucleotide binding pocket

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Eukaryotic DNA replication control: lock and load, then fire

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Conformational spread: the propagation of allosteric states in large multiprotein complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Stepwise assembly of initiation proteins at budding yeast replication origins in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Phosphate release in F1-ATPase catalytic cycle follows ADP release.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Simultaneous electrophoretic analysis of proteins of very high and low molecular weights using low-percentage acrylamide gel and a gradient SDS-PAGE gel.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Conformational changes induced by nucleotide binding in Cdc6/ORC from Aeropyrum pernix

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Functions of sensor 1 and sensor 2 regions of Saccharomyces cerevisiae Cdc6p in vivo and in vitro

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Mutational analysis of conserved sequence motifs in the budding yeast Cdc6 protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3597701

Molecular substructure of a viral receptor-recognition protein. The gp17 tail-fiber of bacteriophage T7

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23376927

12 December 2020

inferred from PubMed ID database lookup

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23376927

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1093/NAR/GKT043

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

release_rndbreozlff3xo2lnv47joi5kq

23 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rndbreozlff3xo2lnv47joi5kq

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2 references

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23376927%20AND%20SRC:MED&resulttype=core&format=json