(Q34549573)

3 August 2017

Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication (English)

1 reference

3 August 2017

Christian Speck

1

1 reference

PubMed ID

17314092

3 August 2017

Bruce Stillman

series ordinal

2

1 reference

PubMed ID

17314092

3 August 2017

language of work or name

English

0 references

publication date

21 February 2007

1 reference

Journal of Biological Chemistry

3 August 2017

1 reference

3 August 2017

282

1 reference

3 August 2017

11705-11714

1 reference

3 August 2017

16

1 reference

Genome-wide mapping of ORC and Mcm2p binding sites on tiling arrays and identification of essential ARS consensus sequences in S. cerevisiae

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Genome-wide characterization of fission yeast DNA replication origins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Evolutionary relationships and structural mechanisms of AAA+ proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Genome-wide analysis of re-replication reveals inhibitory controls that target multiple stages of replication initiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

A genomic view of eukaryotic DNA replication.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

DNA replication origins in the Schizosaccharomyces pombe genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Studies of the properties of human origin recognition complex and its Walker A motif mutants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The replicon revisited: an old model learns new tricks in metazoan chromosomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

DNA topology, not DNA sequence, is a critical determinant for Drosophila ORC-DNA binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Analysis on origin recognition complex containing Orc5p with defective Walker A motif

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Sequence-independent DNA binding and replication initiation by the human origin recognition complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Differential DNA affinity specifies roles for the origin recognition complex in budding yeast heterochromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The bacterial replication initiator DnaA. DnaA and oriC, the bacterial mode to initiate DNA replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

DNA replication in eukaryotic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The B2 element of the Saccharomyces cerevisiae ARS1 origin of replication requires specific sequences to facilitate pre-RC formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Stepwise assembly of initiation proteins at budding yeast replication origins in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Cdc6 protein causes premature entry into S phase in a mammalian cell-free system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

High-affinity binding sites for the initiator protein DnaA on the chromosome of Escherichia coli.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Interaction between yeast Cdc6 protein and B-type cyclin/Cdc28 kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Initiation complex assembly at budding yeast replication origins begins with the recognition of a bipartite sequence by limiting amounts of the initiator, ORC

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The origin recognition complex in silencing, cell cycle progression, and DNA replication.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

Purified dnaA protein in initiation of replication at the Escherichia coli chromosomal origin of replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

A yeast chromosomal origin of DNA replication defined by multiple functional elements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3033201

The fission yeast cdc18+ gene product couples S phase to START and mitosis.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

Mutational analysis of conserved sequence motifs in the budding yeast Cdc6 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

Functions of sensor 1 and sensor 2 regions of Saccharomyces cerevisiae Cdc6p in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

DNA replication origins fire stochastically in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

Competence to replicate in the unfertilized egg is conferred by Cdc6 during meiotic maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700399200

p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17314092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17314092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[On the regulation of DNA synthesis in bacteria: the hypothesis of the replicon.]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17314092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M700399200

1 reference

3 August 2017

1 reference

3 August 2017

1 reference

PubMed ID

17314092