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Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer
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scholarly article
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stated in
PubMed
review article
1 reference
stated in
Europe PubMed Central
title
Emerging evidence on the role of the Hippo/YAP pathway in liver physiology and cancer
(English)
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stated in
PubMed
main subject
physiology
0 references
author
Dean Yimlamai
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
Fernando Camargo
series ordinal
3
object named as
Fernando D Camargo
1 reference
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
author name string
Brendan H Fowl
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
language of work or name
English
1 reference
stated in
PubMed
publication date
December 2015
1 reference
stated in
PubMed
published in
Journal of Hepatology
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
volume
63
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
issue
6
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
page(s)
1491-1501
1 reference
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
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Hippo pathway activity influences liver cell fate
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Bile acids activate YAP to promote liver carcinogenesis
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A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.
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29 September 2017
The Ets transcription factor GABP is a component of the hippo pathway essential for growth and antioxidant defense.
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29 September 2017
Hepatic stem cell niches
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29 September 2017
Differentiation of progenitors in the liver: a matter of local choice
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29 September 2017
Robust cellular reprogramming occurs spontaneously during liver regeneration.
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29 September 2017
Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma
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29 September 2017
Restriction of intestinal stem cell expansion and the regenerative response by YAP.
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Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice
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Next generation sequencing reveals genetic landscape of hepatocellular carcinomas
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Yes-associated protein regulates the hepatic response after bile duct ligation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Cholangiocarcinomas can originate from hepatocytes in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Expression of Yes-associated protein modulates Survivin expression in primary liver malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Deregulation of Hippo kinase signalling in human hepatic malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Loss of tumor suppressor Merlin in advanced breast cancer is due to post-translational regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Hippo pathway effector Yap is an ovarian cancer oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
The Hippo-YAP pathway: new connections between regulation of organ size and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Role of Lgl/Dlg/Scribble in the regulation of epithelial junction, polarity and growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Stem cells, cell transplantation and liver repopulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
29 September 2017
Organ size control is dominant over Rb family inactivation to restrict proliferation in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
2 June 2018
Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
2 June 2018
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
2 June 2018
Notch signaling controls liver development by regulating biliary differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
2 June 2018
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
2 June 2018
Dual role of YAP and TAZ in renewal of the intestinal epithelium.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
27 November 2018
Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
27 November 2018
Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
27 November 2018
Differential expression of Yes-associated protein is correlated with expression of cell cycle markers and pathologic TNM staging in non-small-cell lung carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
27 November 2018
Wnt signaling and hepatocarcinogenesis: the hepatoblastoma model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
27 November 2018
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654680
retrieved
27 November 2018
Dynamic alterations in Hippo signaling pathway and YAP activation during liver regeneration
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26226451
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Acute portal hypertension reflecting shear stress as a trigger of liver regeneration following partial hepatectomy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26226451
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differences in Yes-associated protein and mRNA levels in regenerating liver and hepatocellular carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26226451
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26226451
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JHEP.2015.07.008
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3819453
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
OpenCitations bibliographic resource ID
3819453
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3819453
PMC publication ID
4654680
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3819453
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
PubMed publication ID
26226451
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3819453
stated in
Europe PubMed Central
PMC publication ID
4654680
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26226451%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 June 2020
ResearchGate publication ID
280583880
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