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Molecular heterogeneity in glioblastoma: potential clinical implications
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scholarly article
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stated in
PubMed
review article
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stated in
Europe PubMed Central
title
Molecular heterogeneity in glioblastoma: potential clinical implications
(English)
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stated in
PubMed
main subject
heterogeneity
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based on heuristic
inferred from title
glioblastoma
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based on heuristic
inferred from title
author name string
Nicole Renee Parker
series ordinal
1
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stated in
Crossref
Peter Khong
series ordinal
2
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stated in
Crossref
Jonathon Fergus Parkinson
series ordinal
3
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stated in
Crossref
Viive Maarika Howell
series ordinal
4
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stated in
Crossref
Helen Ruth Wheeler
series ordinal
5
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stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
3 March 2015
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stated in
PubMed
published in
Frontiers in Oncology
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stated in
Crossref
volume
5
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stated in
PubMed
page(s)
55
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PubMed
cites work
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20 March 2017
Intratumor heterogeneity: evolution through space and time
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20 March 2017
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Will kinase inhibitors make it as glioblastoma drugs?
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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
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The somatic genomic landscape of glioblastoma
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Neural stem cells and the origin of gliomas
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The clonal evolution of tumor cell populations
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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
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Intra-tumour heterogeneity: a looking glass for cancer?
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7 April 2017
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
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Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
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29 September 2017
MGMT testing--the challenges for biomarker-based glioma treatment
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29 September 2017
Hif-1α and Hif-2α differentially regulate Notch signaling through competitive interaction with the intracellular domain of Notch receptors in glioma stem cells
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Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02
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29 September 2017
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29 September 2017
Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma
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29 September 2017
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29 September 2017
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.
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Rindopepimut: an evidence-based review of its therapeutic potential in the treatment of EGFRvIII-positive glioblastoma
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Epidermal growth factor receptor: a re-emerging target in glioblastoma
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Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial
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Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
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Characterizing mutational heterogeneity in a glioblastoma patient with double recurrence.
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Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
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Temozolomide in elderly patients with newly diagnosed glioblastoma and poor performance status: an ANOCEF phase II trial
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29 September 2017
Heterogeneity maintenance in glioblastoma: a social network
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29 September 2017
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Rindopepimut, a 14-mer injectable peptide vaccine against EGFRvIII for the potential treatment of glioblastoma multiforme.
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29 September 2017
DecisionDx-GBM Gene Expression Assay for Prognostic Testing in Glioblastoma Multiform
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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?
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29 September 2017
Tumor heterogeneity: causes and consequences
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29 September 2017
A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells
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Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
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29 September 2017
Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy
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29 September 2017
Identification of regions correlating MGMT promoter methylation and gene expression in glioblastomas
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Phase II study of imatinib in patients with recurrent gliomas of various histologies: a European Organisation for Research and Treatment of Cancer Brain Tumor Group Study
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Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
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MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma
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The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma
1 reference
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21 January 2018
Prognostic effect of epidermal growth factor receptor and EGFRvIII in glioblastoma multiforme patients.
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Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy
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21 January 2018
Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma
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Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.
1 reference
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Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity.
1 reference
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Crossref
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21 January 2018
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
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Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas
1 reference
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reference URL
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retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.3389/FONC.2015.00055
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1097565
OpenCitations bibliographic resource ID
1097565
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1097565
PMCID
4347445
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1097565
PubMed ID
25785247
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1097565
ResearchGate publication ID
273784398
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