(Q28115210)

English

Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate

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scholarly article

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PubMed publication ID

3 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate (English)

2 references

PubMed publication ID

3 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

phosphorylation

0 references

Protein tyrosine kinase 6

1 reference

GOA release 2020-03-11

protein tyrosine kinase activity

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Angela L. Tyner

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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object named as

John M Asara

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Yu Zheng

1

2 references

PubMed publication ID

3 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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publication date

14 November 2011

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Europe PubMed Central

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16 January 2020

Journal of Biological Chemistry

2 references

PubMed publication ID

3 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

287

2 references

PubMed publication ID

3 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1

2 references

PubMed publication ID

3 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

148-158

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3249066/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells

1 reference

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Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability

1 reference

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20 March 2017

Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6

1 reference

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1 reference

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1 reference

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1 reference

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20 March 2017

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

1 reference

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20 March 2017

Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

1 reference

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20 March 2017

Structural basis of the auto-inhibition mechanism of nonreceptor tyrosine kinase PTK6

1 reference

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20 March 2017

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Met receptors induce Sam68-dependent cell migration by activation of alternate extracellular signal-regulated kinase family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Brk is coamplified with ErbB2 to promote proliferation in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Role of the Brk SH3 domain in substrate recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells

1 reference

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20 March 2017

Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

BRK/Sik expression in the gastrointestinal tract and in colon tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Invadopodia: specialized cell structures for cancer invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

20 March 2017

The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin

1 reference

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29 September 2017

Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

29 September 2017

ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells.

1 reference

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29 September 2017

Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

29 September 2017

PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

29 September 2017

Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3249066

29 September 2017

Oncogenic functions of PTK6 are enhanced by its targeting to plasma membrane but abolished by its targeting to nucleus

1 reference

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Multiple regulatory inputs converge on cortactin to control invadopodia biogenesis and extracellular matrix degradation.

1 reference

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Solid-phase peptide library synthesis on HiCore resin for screening substrate specificity of Brk protein tyrosine kinase

1 reference

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Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells

1 reference

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The BRK tyrosine kinase is expressed in high-grade serous carcinoma of the ovary

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Tyrosine kinase gene expression in the mouse small intestine.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.298117

21 January 2018

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.298117

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.298117

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22084245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22084245

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.298117

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22084245%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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