(Q34659926)

3 August 2017

title

Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells (English)

1 reference

3 August 2017

1 reference

Angela L Tyner

4

0 references

author name string

Patrick M Brauer

series ordinal

1

1 reference

3 August 2017

Yu Zheng

series ordinal

2

1 reference

3 August 2017

Lin Wang

series ordinal

3

1 reference

3 August 2017

publication date

30 October 2010

1 reference

3 August 2017

number of pages

10

1 reference

inferred from page(s)

published in

Cell Cycle

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3 August 2017

volume

9

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3 August 2017

issue

20

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3 August 2017

page(s)

4190-4199

1 reference

describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3055202/fullTextXML

inferred from PubMed Central ID database lookup

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7 July 2018

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7 July 2018

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7 July 2018

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Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion

7 July 2018

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7 July 2018

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Brk is coamplified with ErbB2 to promote proliferation in breast cancer

7 July 2018

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7 July 2018

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Nuclear trafficking of pro-apoptotic kinases in response to DNA damage

7 July 2018

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The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor

7 July 2018

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Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6

7 July 2018

1 reference

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Targeting the RNA-binding protein Sam68 as a treatment for cancer?

7 July 2018

1 reference

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Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis

7 July 2018

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Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells

7 July 2018

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The role of Src in prostate cancer

7 July 2018

1 reference

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PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.

7 July 2018

1 reference

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The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Identification of STAT3 as a specific substrate of breast tumor kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

RACK1 has the nerve to act: structure meets function in the nervous system.

7 July 2018

1 reference

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Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression

7 July 2018

1 reference

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Role of breast tumour kinase in the in vitro differentiation of HaCaT cells.

7 July 2018

1 reference

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The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Leucine-rich nuclear-export signals: born to be weak

7 July 2018

1 reference

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Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas

7 July 2018

1 reference

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Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Regulated association of protein kinase B/Akt with breast tumor kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

RACK1 regulates Src-mediated Sam68 and p190RhoGAP signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

The RACK1 scaffold protein: a dynamic cog in cell response mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

RACK1: a novel substrate for the Src protein-tyrosine kinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

ERK2 enters the nucleus by a carrier-independent mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

BRK/Sik expression in the gastrointestinal tract and in colon tumors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Assignment of the human PTK6 gene encoding a non-receptor protein tyrosine kinase to 20q13.3 by fluorescence in situ hybridization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Identification of a novel nuclear localization signal in Sam68.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Nucleocytoplasmic transport: signals, mechanisms and regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Selective growth arrest and phenotypic reversion of prostate cancer cells in vitro by nontoxic pharmacological concentrations of phenylacetate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Tyrosine kinase gene expression in the mouse small intestine.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3055202

Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.9.20.13518

Identification of a C-terminal region that is required for the nuclear translocation of ERK2 by passive diffusion.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.9.20.13518

Mutations in ERK2 Binding Sites Affect Nuclear Entry

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20953141

12 December 2020

inferred from PubMed ID database lookup

Identification of amplified DNA sequences in breast cancer and their organization within homogeneously staining regions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20953141

12 December 2020

inferred from PubMed ID database lookup

BRK tyrosine kinase expression in a high proportion of human breast carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20953141

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.4161/CC.9.20.13518

1 reference

3 August 2017

1 reference

3 August 2017

1 reference