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TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres
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scholarly article
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
title
TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres
(English)
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
main subject
Telomeric repeat binding factor 2
1 reference
stated in
GOA release 2020-03-11
X-ray repair cross complementing 5
1 reference
stated in
GOA release 2020-03-11
X-ray repair cross complementing 6
1 reference
stated in
GOA release 2020-03-11
protein-containing complex binding
1 reference
stated in
GOA release 2020-03-11
author name string
Albert Ribes-Zamora
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
Sandra M. Indiviglio
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
Ivana Mihalek
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
Christopher L. Williams
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
Alison A. Bertuch
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
publication date
17 October 2013
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stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
published in
Cell Reports
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
volume
5
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
page(s)
194–206
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stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
issue
1
1 reference
stated in
PubMed
PubMed ID
24095731
retrieved
4 January 2017
describes a project that uses
ImageQuant
1 reference
stated in
Europe PubMed Central
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3984498/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Mammalian telomeres end in a large duplex loop
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Ku is associated with the telomere in mammals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Identification of human Rap1: implications for telomere evolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Interaction of human Ku70 with TRF2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Ku recruits XLF to DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
In vivo stoichiometry of shelterin components
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Control of telomere length by the human telomeric protein TRF1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
The human Rap1 protein complex and modulation of telomere length
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Synapsis of DNA ends by DNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
HADDOCK: a protein-protein docking approach based on biochemical or biophysical information
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
TRF2 Protects Human Telomeres from End-to-End Fusions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Ku86 represses lethal telomere deletion events in human somatic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Mammalian Rap1 controls telomere function and gene expression through binding to telomeric and extratelomeric sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
Pathways of DNA double-strand break repair during the mammalian cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
20 March 2017
How shelterin protects mammalian telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
7 April 2017
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
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7 April 2017
A two-step mechanism for TRF2-mediated chromosome-end protection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Removal of shelterin reveals the telomere end-protection problem
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Mutually exclusive binding of telomerase RNA and DNA by Ku alters telomerase recruitment model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Ku regulates signaling to DNA damage response pathways through the Ku70 von Willebrand A domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Ku must load directly onto the chromosome end in order to mediate its telomeric functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Human telomeric proteins occupy selective interstitial sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Distinct functions of POT1 at telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Electron microscopy reconstructions of DNA repair complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
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29 September 2017
Ku: a multifunctional protein involved in telomere maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
The double life of the Ku protein: facing the DNA breaks and the extracellular environment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
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29 September 2017
PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
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29 September 2017
Ku acts in a unique way at the mammalian telomere to prevent end joining
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
DNA looping by Ku and the DNA-dependent protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
29 September 2017
Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
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29 September 2017
Human RAP1 inhibits non-homologous end joining at telomeres
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
2 June 2018
How shelterin solves the telomere end-protection problem
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
27 November 2018
Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3984498
retrieved
27 November 2018
Erythropoietin receptor activation by a ligand-induced conformation change
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24095731
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24095731
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24095731
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous recombination
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24095731
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CELREP.2013.08.040
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2551241
OpenCitations bibliographic resource ID
2551241
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2551241
PMCID
3984498
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2551241
PubMed ID
24095731
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2551241
ResearchGate publication ID
257462621
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