(Q28118029)

4 January 2017

title

F-box protein 7 mutations promote protein aggregation in mitochondria and inhibit mitophagy (English)

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positive regulation of autophagy of mitochondrion

4 January 2017

main subject

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GOA release 2020-03-11

F-box protein 7

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GOA release 2020-03-11

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13

Mitchell Kim Peng Lai

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4 January 2017

Zhi Dong Zhou

1

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4 January 2017

Shao Ping Xie

2

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4 January 2017

Sushmitha Sathiyamoorthy

3

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4 January 2017

Wuan Ting Saw

4

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4 January 2017

Tan Ye Sing

5

1 reference

4 January 2017

Shin Hui Ng

6

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4 January 2017

Heidi Pek Hup Chua

7

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4 January 2017

Alyssa Mei Yan Tang

8

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4 January 2017

Fathima Shaffra

9

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4 January 2017

Zeng Li

10

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4 January 2017

Hongyan Wang

11

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4 January 2017

Patrick Ghim Hoe Ho

12

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4 January 2017

Dario C. Angeles

14

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4 January 2017

Tit Meng Lim

15

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4 January 2017

Eng-King Tan

16

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4 January 2017

publication date

15 November 2015

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4 January 2017

published in

Human Molecular Genetics

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4 January 2017

volume

24

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4 January 2017

issue

22

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4 January 2017

page(s)

6314–6330

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Parkinson's disease: mechanisms and models

4 January 2017

cites work

1 reference

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21 January 2018

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PLA2G6 gene mutation in autosomal recessive early-onset parkinsonism in a Chinese cohort

21 January 2018

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

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Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

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The ubiquitin pathway in Parkinson's disease

21 January 2018

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Molecular genetic pathways in Parkinson's disease: a review

21 January 2018

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FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

21 January 2018

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Genome-wide linkage analysis of a Parkinsonian-pyramidal syndrome pedigree by 500 K SNP arrays

21 January 2018

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Identification of a family of human F-box proteins

21 January 2018

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A family of mammalian F-box proteins

21 January 2018

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The utility F-box for protein destruction

21 January 2018

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SCF-mediated protein degradation and cell cycle control

21 January 2018

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Roles of ubiquitin-mediated proteolysis in cell cycle control

21 January 2018

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FBXO7 immunoreactivity in α-synuclein-containing inclusions in Parkinson disease and multiple system atrophy

21 January 2018

1 reference

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Fbx7 functions in the SCF complex regulating Cdk1-cyclin B-phosphorylated hepatoma up-regulated protein (HURP) proteolysis by a proline-rich region

21 January 2018

1 reference

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The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Fbxo7 gets proactive with cyclin D/cdk6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy

21 January 2018

1 reference

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Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant

21 January 2018

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Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress

21 January 2018

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α-Synuclein fate is determined by USP9X-regulated monoubiquitination

21 January 2018

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Mitophagy in neurodegeneration and aging

21 January 2018

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Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

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After the banquet: mitochondrial biogenesis, mitophagy, and cell survival

21 January 2018

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Parkin and PINK1: much more than mitophagy

21 January 2018

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21 January 2018

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Cross-compartment protection by SOD1.

21 January 2018

1 reference

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Alpha-synuclein and neurodegenerative diseases

21 January 2018

1 reference

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Oxidized/misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis?

21 January 2018

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Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases

21 January 2018

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The mitochondrial UPR - protecting organelle protein homeostasis

21 January 2018

1 reference

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Mitochondrial enzymes are protected from stress-induced aggregation by mitochondrial chaperones and the Pim1/LON protease

21 January 2018

1 reference

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The mitochondrial protease AFG3L2 is essential for axonal development

21 January 2018

1 reference

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Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease

21 January 2018

1 reference

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Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria

21 January 2018

1 reference

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Pyrroloquinoline quinone (PQQ) prevents fibril formation of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Intracellular Abeta and C99 aggregates induce mitochondria-dependent cell death in human neuroglioma H4 cells through recruitment of the 20S proteasome subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Mutant PINK1 upregulates tyrosine hydroxylase and dopamine levels, leading to vulnerability of dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Iron species-mediated dopamine oxidation, proteasome inhibition, and dopaminergic cell demise: implications for iron-related dopaminergic neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

Antioxidant activity applying an improved ABTS radical cation decolorization assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDV340

21 January 2018

Identifiers

DOI

10.1093/HMG/DDV340

0 references

1 reference