(Q28179222)

8

object named as

A Jennifer Morton

0 references

author name string

J Michael Edwardson

1

0 references

Belvin Gong

3

0 references

Andreas Wyttenbach

4

0 references

Jihong Bai

5

0 references

Meyer B Jackson

6

0 references

Edwin R Chapman

Journal of Biological Chemistry

7

0 references

language of work or name

English

0 references

publication date

15 August 2003

0 references

published in

0 references

volume

278

0 references

issue

33

0 references

page(s)

30849-53

0 references

cites work

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Inactivation of the mouse Huntington's disease gene homolog Hdh

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

A huntingtin-associated protein enriched in brain with implications for pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Clinical and neuropathologic assessment of severity in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Motor disorder in Huntington's disease begins as a dysfunction in error feedback control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Cognitive scores in carriers of Huntington's disease gene compared to noncarriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Evidence for specific cognitive deficits in preclinical Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Progressive depletion of complexin II in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Membrane fusion and exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Abnormalities in the synaptic vesicle fusion machinery in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Complexins: cytosolic proteins that regulate SNAP receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Localization of rabbit huntingtin using a new panel of monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Rapid and selective binding to the synaptic SNARE complex suggests a modulatory role of complexins in neuroexocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Regulatory roles of complexins in neurotransmitter release from mature presynaptic nerve terminals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Reduced hippocampal LTP in mice lacking a presynaptic protein: complexin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Complexins regulate a late step in Ca2+-dependent neurotransmitter release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Action of complexin on SNARE complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Immunohistochemical distribution of the two isoforms of synaphin/complexin involved in neurotransmitter release: localization at the distinct central nervous system regions and synaptic types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Transfection analysis of functional roles of complexin I and II in the exocytosis of two different types of secretory vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200

Complexin regulates the closure of the fusion pore during regulated vesicle exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M304615200