(Q28201470)

1

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C Lecoq-Lafon

2

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S Chrétien

3

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S Zompi

4

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S Fichelson

5

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O Muller

6

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F Porteu

7

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I Dusanter-Fourt

8

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S Gisselbrecht

9

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P Mayeux

10

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C Lacombe

Mechanism of activation and function of protein kinase B.

11

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language of work or name

English

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publication date

26 April 2001

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published in

Oncogene

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volume

20

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page(s)

2197-204

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issue

18

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

PI3K: downstream AKTion blocks apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Affinity, specificity, and kinetics of the interaction of the SHC phosphotyrosine binding domain with asparagine-X-X-phosphotyrosine motifs of growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

cMpl ligand is a humoral regulator of megakaryocytopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Engagement of Gab1 and Gab2 in erythropoietin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Recognition and specificity in protein tyrosine kinase-mediated signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317

Characterization of mpl cytoplasmic domain sequences required for myeloproliferative leukemia virus pathogenicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204317