(Q28201680)

ORCID Public Data File 2021

Karen Laky

3

object named as

Karen Laky

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author name string

Meir H Scheinfeld

1

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Enrico Ghersi

2

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B J Fowlkes

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

15 November 2002

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published in

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volume

277

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issue

46

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page(s)

44195-201

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cites work

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

It all sticks together--the APP-related family of proteins and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The presenilins in Alzheimer's disease--proteolysis holds the key.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The gene for the amyloid precursor-like protein APLP2 is assigned to human chromosome 11q23-q25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Selective localization of amyloid precursor-like protein 1 in the cerebral cortex postsynaptic density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Caspase cleavage of members of the amyloid precursor family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The regions of the Fe65 protein homologous to the phosphotyrosine interaction/phosphotyrosine binding domain of Shc bind the intracellular domain of the Alzheimer's amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Immunohistochemical and in situ analysis of amyloid precursor-like protein-1 and amyloid precursor-like protein-2 expression in Alzheimer disease and aged control brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Metabolism of the amyloid precursor-like protein 2 in MDCK cells. Polarized trafficking occurs independent of the chondroitin sulfate glycosaminoglycan chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200

Presenilin-1 and -2 are molecular targets for gamma-secretase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208110200