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The calpain family and human disease
scientific article (publication date: August 2001)
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Europe PubMed Central
PubMed publication ID
11516996
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
review article
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Europe PubMed Central
title
The calpain family and human disease
(English)
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Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author
Kevin K W Wang
series ordinal
2
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Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
author name string
Y Huang
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1
1 reference
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Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
language of work or name
English
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publication date
1 August 2001
1 reference
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Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Trends in Molecular Medicine
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Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
7
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
355-362
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
cites work
Complete amino acid sequence of the large subunit of the low-Ca2+-requiring form of human Ca2+-activated neutral protease (muCANP) deduced from its cDNA sequence
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
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inferred from DOI database lookup
Molecular cloning of the cDNA for the large subunit of the high-Ca2+-requiring form of human Ca2+-activated neutral protease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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inferred from DOI database lookup
Evolutionary origin of a calcium-dependent protease by fusion of genes for a thiol protease and a calcium-binding protein?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Crystal structure of calpain reveals the structural basis for Ca(2+)-dependent protease activity and a novel mode of enzyme activation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Crystal structure of calcium bound domain VI of calpain at 1.9 Å resolution and its role in enzyme assembly, regulation, and inhibitor binding
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain and caspase: can you tell the difference?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the mouse mu-calpain gene reveals an essential role in platelet function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Identification and characterization of a retina-specific calpain (Rt88) from rat.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning and characterization of a novel tissue-specific calpain predominantly expressed in the digestive tract
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of two novel genes, down-regulated in gastric cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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CAPN11: A calpain with high mRNA levels in testis and located on chromosome 6
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
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Identification of a Novel, Tissue-Specific Calpainhtra-3;a Human Homologue of theCaenorhabditis elegansSex Determination Gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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inferred from DOI database lookup
A New Subfamily of Vertebrate Calpains Lacking a Calmodulin-Like Domain: Implications for Calpain Regulation and Evolution
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic organization of mouse Capn5 and Capn6 genes confirms that they are a distinct calpain subfamily
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Structure and physiological function of calpains
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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inferred from DOI database lookup
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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inferred from DOI database lookup
CAPN 8: isolation of a new mouse calpain-isoenzyme
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Calpain inhibition: an overview of its therapeutic potential
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
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Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Immunohistochemical Study of Calpain-Mediated Breakdown Products to α-Spectrin Following Controlled Cortical Impact Injury in the Rat
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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mu-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
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inferred from DOI database lookup
New aspect of the research on limb-girdle muscular dystrophy 2A: a molecular biologic and biochemical approach to pathology
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
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Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
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Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased sensitivity of lens-specific calpain Lp82 to calpastatin inhibitor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of Calpain in Lens: A Review and Proposed Mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
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Beta-crystallins insolubilized by calpain II in vitro contain cleavage sites similar to beta-crystallins insolubilized during cataract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Superior prevention of calcium ionophore cataract by E64d
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cysteine protease inhibitor E64 reduces the rate of formation of selenite cataract in the whole animal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium ionophore induced proteolysis and cataract: inhibition by cell permeable calpain antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
SJA6017, a newly synthesized peptide aldehyde inhibitor of calpain: amelioration of cataract in cultured rat lenses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The involvement of calpain-dependent proteolysis of the tumor suppressor NF2 (merlin) in schwannomas and meningiomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca(2+)-dependent proteinases (calpains) and muscle cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SOLH, a human homologue of the Drosophila melanogaster small optic lobes gene is a member of the calpain and zinc-finger gene families and maps to human chromosome 16p13.3 near CATM (cataract with microphthalmia)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of calpain I messenger RNA in human renal cell carcinoma: correlation with lymph node metastasis and histological type
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ca²+;-Dependent Neutral Protease (Calpain) Activity in Breast Cancer Tissue and Estrogen Receptor Status
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antisense RNA-mediated deficiency of the calpain protease, nCL-4, in NIH3T3 cells is associated with neoplastic transformation and tumorigenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotoxicity induces cleavage of p35 to p25 by calpain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain-mediated degradation of p35 to p25 in postmortem human and rat brains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902049-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1471-4914(01)02049-4
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
904241
stated in
Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
OpenCitations bibliographic resource ID
904241
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
904241
PubMed publication ID
11516996
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
904241
stated in
Europe PubMed Central
PubMed publication ID
11516996
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11516996%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
ResearchGate publication ID
11828639
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