(Q28240025)

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VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

scientific article (publication date: August 2011)

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Europe PubMed Central

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3 February 2020

VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation (English)

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3 February 2020

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Caroline Pellet-Many

2

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3 February 2020

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Birger Herzog

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3 February 2020

Gary Britton

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3 February 2020

Basil Hartzoulakis

4

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3 February 2020

Ian C Zachary

5

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3 February 2020

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8 June 2011

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3 February 2020

Molecular Biology of the Cell

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3 February 2020

22

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3 February 2020

15

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3 February 2020

2766-2776

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3 February 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

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Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells

1 reference

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Structural basis for ligand and heparin binding to neuropilin B domains

1 reference

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The vascular endothelial growth factor (VEGF) family: angiogenic factors in health and disease

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1 reference

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Neuropilin-1 binds vascular endothelial growth factor 165, placenta growth factor-2, and heparin via its b1b2 domain

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1 reference

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1 reference

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Genomic organization of human neuropilin-1 and neuropilin-2 genes: identification and distribution of splice variants and soluble isoforms

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20 March 2017

Synectin, syndecan-4 cytoplasmic domain binding PDZ protein, inhibits cell migration

1 reference

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20 March 2017

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

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20 March 2017

Cloning and characterization of neuropilin-1-interacting protein: a PSD-95/Dlg/ZO-1 domain-containing protein that interacts with the cytoplasmic domain of neuropilin-1

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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

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20 March 2017

Neuropilin is a semaphorin III receptor

1 reference

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Neuropilin is a receptor for the axonal chemorepellent Semaphorin III

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Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

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Focal adhesion kinase is required for blood vessel morphogenesis

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VEGF165 mediates formation of complexes containing VEGFR-2 and neuropilin-1 that enhance VEGF165-receptor binding

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Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1.

1 reference

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Neuropilins: structure, function and role in disease.

1 reference

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1 reference

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Transmembrane domain interactions control biological functions of neuropilin-1

1 reference

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Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities

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A requirement for neuropilin-1 in embryonic vessel formation.

1 reference

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1 reference

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1 reference

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The role of phosphatidylinositol 3-kinase in vascular endothelial growth factor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21653826

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A dominant negative receptor for specific secreted semaphorins is generated by deleting an extracellular domain from neuropilin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21653826

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Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/21653826

12 December 2020

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Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/21653826

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based on heuristic

inferred from PubMed ID database lookup

Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/21653826

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21653826

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inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E09-12-1061

2 references

Consolidated OpenCitations Corpus – April 2017

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3 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653826%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21653826%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

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