(Q28251165)

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Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols

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Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols (English)

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protein ubiquitination

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based on heuristic

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author name string

Bao-Liang Song

1

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Russell A DeBose-Boyd

2

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language of work or name

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publication date

1 September 2006

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Journal of Biological Chemistry

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281

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35

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25054-61

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Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

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Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2.

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Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

1 reference

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Protein sensors for membrane sterols

1 reference

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21 January 2018

Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol

1 reference

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21 January 2018

Topology of SREBP cleavage-activating protein, a polytopic membrane protein with a sterol-sensing domain

1 reference

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21 January 2018

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

1 reference

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21 January 2018

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

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Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Transport-Dependent Proteolysis of SREBP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

1 reference

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21 January 2018

Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol

1 reference

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Tocotrienols: Vitamin E beyond tocopherols

1 reference

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Tocotrienol: a review of its therapeutic potential

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

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Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status

1 reference

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Vitamin E activates gene expression via the pregnane X receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

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Hypocholesterolemic activity of synthetic and natural tocotrienols

1 reference

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The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

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https://api.crossref.org/works/10.1074%2FJBC.M605575200

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Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

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Ubiquitin-aldehyde: a general inhibitor of ubiquitin-recycling processes

1 reference

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A new endogenous natriuretic factor: LLU-alpha

1 reference

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21 January 2018

Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Cytochrome P450 omega-hydroxylase pathway of tocopherol catabolism. Novel mechanism of regulation of vitamin E status

1 reference

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21 January 2018

Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605575200

21 January 2018

Discovery, characterization, and significance of the cytochrome P450 omega-hydroxylase pathway of vitamin E catabolism

1 reference

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21 January 2018

Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: implication to the molecular mechanism of their antioxidant potency

1 reference

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21 January 2018

HMG-CoA reductase inhibitors

1 reference

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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

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Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease

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Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase

1 reference

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21 January 2018

Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers

1 reference

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21 January 2018

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

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Bisphosphonates and atherosclerosis

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Identifiers

10.1074/JBC.M605575200

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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