(Q44620965)

English

Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol

scientific article published on 16 October 2003

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

geranylgeraniol

1 reference

based on heuristic

inferred from title

protein ubiquitination

1 reference

based on heuristic

inferred from title

3

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Joseph L. Goldstein

4

object named as

Joseph L Goldstein

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

author name string

Navdar Sever

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Bao-Liang Song

2

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Michael S Brown

5

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Russell A DeBose-Boyd

6

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

language of work or name

0 references

publication date

16 October 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

number of pages

12

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

278

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PubMed publication ID

4 December 2017

52

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Europe PubMed Central

PubMed publication ID

4 December 2017

52479-52490

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Immunological evidence for eight spans in the membrane domain of 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for enzyme degradation in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

ER-associated degradation in protein quality control and cellular regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Transport-Dependent Proteolysis of SREBP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Regulated step in cholesterol feedback localized to budding of SCAP from ER membranes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

The sterol-sensing domain: multiple families, a unique role?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Recurrent G-to-A substitution in a single codon of SREBP cleavage-activating protein causes sterol resistance in three mutant Chinese hamster ovary cell lines.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle

1 reference

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21 January 2018

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Failure to cleave sterol regulatory element-binding proteins (SREBPs) causes cholesterol auxotrophy in Chinese hamster ovary cells with genetic absence of SREBP cleavage-activating protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Analysis of gene function in somatic mammalian cells using small interfering RNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Identification of two mammalian reductases involved in the two-carbon fatty acyl elongation cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Protein prenylation: molecular mechanisms and functional consequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Novel salvage pathway utilizing farnesol and geranylgeraniol for protein isoprenylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Rab GTPases, intracellular traffic and disease.

1 reference

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21 January 2018

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M310053200

21 January 2018

Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi

1 reference

11 October 2022

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19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

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Identifiers

10.1074/JBC.M310053200

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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