(Q28256905)

2

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T Kiyono

3

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M Sawada

4

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S Yoshimura

5

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T Iwama

6

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Y Banno

7

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J Shinoda

8

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N Sakai

Cell Death & Differentiation

9

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language of work or name

English

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publication date

August 2004

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published in

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volume

11

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issue

8

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page(s)

853-61

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cites work

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Apoptosis and cancer drug targeting

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Suicidal tendencies: apoptotic cell death by caspase family proteinases

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Functions of ceramide in coordinating cellular responses to stress

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Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells.

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7 January 2021

Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.

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p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells

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Cell-cycle arrest versus cell death in cancer therapy

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Regulation of p53 downstream genes.

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Apaf-1 is a transcriptional target for E2F and p53

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p53-dependent ceramide response to genotoxic stress

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Ordering of ceramide formation, caspase activation, and mitochondrial changes during CD95- and DNA damage-induced apoptosis

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Enhancement of radiosensitivity of wild-type p53 human glioma cells by adenovirus-mediated delivery of the p53 gene

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Combined radiation and p53 gene therapy of malignant glioma cells

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p53-dependent G1 arrest and p53-independent apoptosis influence the radiobiologic response of glioblastoma

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The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

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A system for stable expression of short interfering RNAs in mammalian cells

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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Acid sphingomyelinase activation requires caspase-8 but not p53 nor reactive oxygen species during Fas-induced apoptosis in human glioma cells

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Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death

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Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein

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The bovine papillomavirus E6 oncoprotein interacts with paxillin and disrupts the actin cytoskeleton.

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The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

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PKN binds and phosphorylates human papillomavirus E6 oncoprotein

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Role for ceramide in cell cycle arrest.

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Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation

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7 January 2021

Ceramide generation in nitric oxide-induced apoptosis. Activation of magnesium-dependent neutral sphingomyelinase via caspase-3.

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7 January 2021

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

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7 January 2021

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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7 January 2021

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

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7 January 2021

TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase

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Ceramide induces activation of the mitochondrial/caspases pathway in Jurkat and SCC61 cells sensitive to gamma-radiation but activation of this sequence is defective in radioresistant SQ20B cells

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7 January 2021

Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells

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7 January 2021

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5

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7 January 2021

TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes

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7 January 2021

Can the life span of human marrow stromal cells be prolonged by bmi-1, E6, E7, and/or telomerase without affecting cardiomyogenic differentiation?

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7 January 2021