(Q28260518)

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Cytochrome P-450 3A4: regulation and role in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Pharmacogenomics: translating functional genomics into rational therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Cytochrome P450 3A and their regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

In vitro and in vivo drug interactions involving human CYP3A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Human drug metabolising cytochrome P450 enzymes: properties and polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

In-vivo phenotyping for CYP3A by a single-point determination of midazolam plasma concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Assignment of the human cytochrome P-450 nifedipine oxidase gene (CYP3A4) to chromosome 7 at band q22.1 by fluorescence in situ hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A gene expression in human gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Pharmacogenomics: the inherited basis for interindividual differences in drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Substrates of human hepatic cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Concise review of the cytochrome P450s and their roles in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

RESPONSE: re: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A4 polymorphisms - potential risk factors for breast and prostate cancer: a huge review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Genetic contribution to variable human CYP3A-mediated metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: evidence for an allelic variant with altered catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A4 promoter variant in Saudi, Ghanaian and Scottish Caucasian populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Effect of age on in vitro triazolam biotransformation in male human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Association of CYP3A4 genotype with treatment-related leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Identification and functional characterization of eight CYP3A4 protein variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Recombinant CYP3A4*17 is defective in metabolizing the hypertensive drug nifedipine, and the CYP3A4*17 allele may occur on the same chromosome as CYP3A5*3, representing a new putative defective CYP3A haplotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A4 gene polymorphisms influence testosterone 6beta-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

The human cytochrome P450 CYP3 locus: assignment to chromosome 7q22-qter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Expression of cytochrome P 450 3A enzymes in human lung: a combined RT-PCR and immunohistochemical analysis of normal tissue and lung tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Expression of cytochrome P450 3A in amphibian, rat, and human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Human prostate CYP3A5: identification of a unique 5'-untranslated sequence and characterization of purified recombinant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Selective expression of CYP3A5 and not CYP3A4 in human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A variation and the evolution of salt-sensitivity variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Association between the CYP3A5 genotype and blood pressure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Roles of divalent metal ions in oxidations catalyzed by recombinant cytochrome P450 3A4 and replacement of NADPH--cytochrome P450 reductase with other flavoproteins, ferredoxin, and oxygen surrogates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Analysis of four residues within substrate recognition site 4 of human cytochrome P450 3A4: role in steroid hydroxylase activity and alpha-naphthoflavone stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Effects of cytochrome b(5) on drug oxidation activities of human cytochrome P450 (CYP) 3As: similarity of CYP3A5 with CYP3A4 but not CYP3A7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Single nucleotide polymorphisms and haplotype frequencies of CYP3A5 in a Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Detection of CYP3A5 allelic variant: a candidate for the polymorphic expression of the protein?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Lipid-lowering response to statins is affected by CYP3A5 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A5*1-carrying graft liver reduces the concentration/oral dose ratio of tacrolimus in recipients of living-donor liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A5 polymorphism and the ethnic differences in cyclosporine pharmacokinetics in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A5 genotype and midazolam clearance in Australian patients receiving chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Increased levels of aflatoxin-albumin adducts are associated with CYP3A5 polymorphisms in The Gambia, West Africa

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Nonsense-mediated mRNA decay in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Genetic variability in CYP3A5 and its possible consequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Genotype???phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Pharmacokinetics of midazolam and 1'-hydroxymidazolam in Chinese with different CYP3A5 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Impact of cytochrome p450 3A5 genetic polymorphism on tacrolimus doses and concentration-to-dose ratio in renal transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Sex is a major determinant of CYP3A4 expression in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Steroid hormone hydroxylase specificities of eleven cDNA-expressed human cytochrome P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

Expression of Cytochrome-P450-3A5 in Escherichia Coli: Effects of 5′ Modification, Purification, Spectral Characterization, Reconstitution Conditions, and Catalytic Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14622416.6.4.357

21 January 2018

Identifiers

DOI

10.1517/14622416.6.4.357

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16004554

1 reference

Consolidated OpenCitations Corpus – April 2017