(Q28261086)

2

0 references

Stephen D Lee

3

0 references

Kristina Sachs-Barrable

4

0 references

Sheila J Thornton

Nature Reviews Drug Discovery

5

0 references

language of work or name

English

0 references

publication date

January 2008

0 references

published in

0 references

volume

7

0 references

issue

1

0 references

page(s)

84-99

0 references

cites work

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

1 reference

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report

31 March 2020

1 reference

Serum high-density lipoprotein cholesterol, metabolic profile, and breast cancer risk

31 March 2020

1 reference

Hypertriglyceridemia as a possible risk factor for prostate cancer.

31 March 2020

1 reference

Serum lipoprotein profile in patients with cancer. A comparison with non-cancer subjects

31 March 2020

1 reference

Hypocholesterolaemia in malignancy due to elevated low-density-lipoprotein-receptor activity in tumour cells: evidence from studies in patients with leukaemia

31 March 2020

1 reference

Uptake of low density lipoproteins by human leukemic cells in vivo: relation to plasma lipoprotein levels and possible relevance for selective chemotherapy

31 March 2020

1 reference

Genomewide scan for familial combined hyperlipidemia genes in finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and apolipoprotein B levels

31 March 2020

1 reference

31 March 2020

Update on dyslipidemia

1 reference

Effects of HIV disease on lipid, glucose and insulin levels: results from a large antiretroviral-naive cohort

31 March 2020

1 reference

Changes in plasma lipoproteins in acute malaria

31 March 2020

1 reference

Alterations of lecithin-cholesterol acyltransferase activity during Plasmodium chabaudi rodent malaria

31 March 2020

1 reference

Hypertriglyceridemia as an indicator of the severity of falciparum malaria in returned travelers: a clinical retrospective study

31 March 2020

1 reference

The influence of lipids on stereoselective pharmacokinetics of halofantrine: Important implications in food-effect studies involving drugs that bind to lipoproteins

31 March 2020

1 reference

A physicochemical basis for the effect of food on the absolute oral bioavailability of halofantrine

31 March 2020

1 reference

Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state

31 March 2020

1 reference

Long-term problems related to immunosuppression.

31 March 2020

1 reference

Consensus development conference on antipsychotic drugs and obesity and diabetes

31 March 2020

1 reference

Pharmacokinetics of Amiodarone in hyperlipidemic and simulated high fat-meal rat models

31 March 2020

1 reference

Insights into the effects of hyperlipoproteinemia on cyclosporine A biodistribution and relationship to renal function

31 March 2020

1 reference

Effect of serum triglyceride concentration on the fluctuation of whole blood concentration of cyclosporin A in patients

31 March 2020

1 reference

High-fat meals increase the clearance of cyclosporine

31 March 2020

1 reference

Effect of food on the pharmacokinetics of cyclosporine in healthy subjects following oral and intravenous administration

31 March 2020

1 reference

Effect of dietary fat on the pharmacokinetics and pharmacodynamics of cyclosporine in kidney transplant recipients

31 March 2020

1 reference

The effect of increased lipoprotein levels on the pharmacokinetics of cyclosporine A in the laboratory rat.

31 March 2020

1 reference

Effect of co-administration of Intralipid on the pharmacokinetics of cyclosporine in the rabbit

31 March 2020

1 reference

Concentrations in serum and distribution in tissue of free and liposomal amphotericin B in rats during continuous intralipid infusion

31 March 2020

1 reference

Effects of hyperlipidemia on the pharmacokinetics of nifedipine in the rat

31 March 2020

1 reference

Pharmacokinetics of halofantrine in man: effects of food and dose size

31 March 2020

1 reference

Parenteral nutrition and cyclosporine: do lipids make a difference? A prospective randomized crossover trial

31 March 2020

1 reference

Comparative pharmacokinetics and pharmacodynamics of propranolol and atenolol in normolipaemic and hyperlipidaemic obese subjects.

31 March 2020

1 reference

Studies on the Pharmacokinetics and Pharmacodynamics of Propranolol in Hyperlipidemia

31 March 2020

1 reference

The hyperlipidemic hamster as a model of experimental atherosclerosis

31 March 2020

1 reference

Canine lipoproteins and atherosclerosis. I. Isolation and characterization of plasma lipoproteins from control dogs

31 March 2020

1 reference

The relationship between plasma high density lipoprotein cholesterol levels and cholesteryl ester transfer protein activity in six species of healthy experimental animals

31 March 2020

1 reference

Emerging indications for the use of cyclosporin in organ transplantation and autoimmunity

31 March 2020

1 reference

Interaction of cyclosporin A with human lipoproteins.

31 March 2020

1 reference

Differences in lipoprotein lipid concentration and composition modify the plasma distribution of cyclosporine

31 March 2020

1 reference

High cyclosporin levels after bone marrow transplantation associated with hypertriglyceridaemia

31 March 2020

1 reference

Cyclosporin leukoencephalopathy induced by intravenous lipid solution

31 March 2020

1 reference

Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol

31 March 2020

1 reference

Transport and metabolism of cyclosporine in isolated rat hepatocytes. The effects of lipids

31 March 2020

1 reference

Lipophilicity in PK design: methyl, ethyl, futile

31 March 2020

1 reference

Exchange of phosphatidylcholine between small unilamellar liposomes and human plasma high-density lipoprotein involves exclusively the phospholipid in the outer monolayer of the liposomal membrane

31 March 2020

1 reference

Role of plasma lipoproteins in modifying the biological activity of hydrophobic drugs

31 March 2020

1 reference

Differences in lipoprotein concentration and composition modify the plasma distribution of free and liposomal annamycin

31 March 2020

1 reference

Plasma lipoprotein distribution of liposomal nystatin is influenced by protein content of high-density lipoproteins.

31 March 2020

1 reference

Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake

31 March 2020

1 reference

Structure and physiologic function of the low-density lipoprotein receptor

31 March 2020

1 reference

The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions

31 March 2020

1 reference

Cell association of liposomes with high fluid anionic phospholipid content is mediated specifically by LDL and its receptor, LDLr

31 March 2020

1 reference

LDL induced association of anionic liposomes with cells and delivery of contents as shown by the increase in potency of liposome dependent drugs

31 March 2020

1 reference

LDL-induced association of anionic liposomes with cells and delivery of contents. II. Interaction of liposomes with cells in serum-containing medium

31 March 2020

1 reference

Low-density lipoprotein receptor-related protein mediates the endocytosis of anionic liposomes in neurons.

31 March 2020

1 reference

Human recombinant apolipoprotein E-enriched liposomes can mimic low-density lipoproteins as carriers for the site-specific delivery of antitumor agents

31 March 2020

1 reference

Synthesis of a lipophilic daunorubicin derivative and its incorporation into lipidic carriers developed for LDL receptor-mediated tumor therapy.

31 March 2020

1 reference

Low-density lipoprotein receptor-mediated delivery of a lipophilic daunorubicin derivative to B16 tumours in mice using apolipoprotein E-enriched liposomes.

31 March 2020

1 reference

Low density lipoprotein and liposome mediated uptake and cytotoxic effect of N4-octadecyl-1-beta-D-arabinofuranosylcytosine in Daudi lymphoma cells

31 March 2020

1 reference

Use of a cholesterol-rich emulsion that binds to low-density lipoprotein receptors as a vehicle for paclitaxel

31 March 2020

1 reference

Cyclosporine, low-density lipoprotein, and cholesterol

31 March 2020

1 reference

The role of lipoproteins in the transport and uptake of cyclosporine and dihydro-tacrolimus into HepG2 and JURKAT cell lines

31 March 2020

1 reference

Serum cholesterol levels and kidney transplantation outcome: attenuation of cyclosporine efficacy?

31 March 2020

1 reference

Effects of low and high density lipoproteins on renal cyclosporine A and cyclosporine G disposition in the isolated perfused rat kidney

31 March 2020

1 reference

Effects of lipoproteins on cyclosporine A toxicity and uptake in LLC-PK1 pig kidney cells

31 March 2020

1 reference

Effect of cyclosporine A on the binding affinity and internalization of low-density lipoproteins in human skin fibroblasts

31 March 2020

1 reference

Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family

31 March 2020

1 reference

Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs

31 March 2020

1 reference

The unfolding story of megalin (gp330): now recognized as a drug receptor

31 March 2020

1 reference

Megalin Deficiency Offers Protection from Renal Aminoglycoside Accumulation

31 March 2020

1 reference

Role of megalin in renal handling of aminoglycosides

31 March 2020

1 reference

Alpha 2-macroglobulin receptor mediates binding and cytotoxicity of plant ribosome-inactivating proteins.

31 March 2020

1 reference

Trichosanthin interacts with and enters cells via LDL receptor family members

31 March 2020

1 reference

Induction of mid-term abortion by trichosanthin in laboratory animals

31 March 2020

1 reference

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

31 March 2020

1 reference

A mutant high-density lipoprotein receptor inhibits proliferation of human breast cancer cells

31 March 2020

1 reference

Decreased toxicity of liposomal amphotericin B due to association of amphotericin B with high-density lipoproteins: role of lipid transfer protein

31 March 2020

1 reference

Differences in the lipoprotein distribution of halofantrine are regulated by lipoprotein apolar lipid and protein concentration and lipid transfer protein I activity: In vitro studies in normolipidemic and dyslipidemic human plasmas

31 March 2020

1 reference

Cyclosporine transfer from low- and high-density lipoproteins is partially influenced by lipid transfer protein I triglyceride transfer activity

31 March 2020

1 reference

Cyclosporine A transfer between high- and low-density lipoproteins: independent from lipid transfer protein I-facilitated transfer of lipoprotein-coated phospholipids because of high affinity of cyclosporine a for the protein component of lipoprotei

31 March 2020

1 reference

Alternative modalities of administering amphotericin B: current issues

31 March 2020

1 reference

Current role of therapy with amphotericin B

31 March 2020

1 reference

Roles of liposome composition and temperature in distribution of amphotericin B in serum lipoproteins

31 March 2020

1 reference

Influence of lipoproteins on renal cytotoxicity and antifungal activity of amphotericin B.

31 March 2020

1 reference

Potential application of plant lipid transfer proteins for drug delivery.

31 March 2020

1 reference

Effects of plasma lipid levels on blood distribution and pharmacokinetics of cyclosporin A

31 March 2020

1 reference

Cholesteryl ester transfer protein: an enigmatic protein

31 March 2020

1 reference

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

31 March 2020

1 reference

Partial suppression of CETP activity beneficially modifies the lipid transfer profile of plasma

31 March 2020

1 reference

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

31 March 2020

1 reference

Low-density lipoprotein subfractions and the long-term risk of ischemic heart disease in men: 13-year follow-up data from the Québec Cardiovascular Study

31 March 2020

1 reference

A receptor-mediated pathway for cholesterol homeostasis

31 March 2020

1 reference

Molecular regulation of HDL metabolism and function: implications for novel therapies

31 March 2020

1 reference

Mechanism of prebeta-HDL formation and activation

31 March 2020

1 reference

Safety, pharmacokinetics, pharmacodynamics, and plasma lipoprotein distribution of eritoran (E5564) during continuous intravenous infusion into healthy volunteers

31 March 2020

1 reference

Primer: Histopathology of calcineurin-inhibitor toxicity in renal allografts

31 March 2020

1 reference

Carrier-Mediated Transport of Thyroid Hormones through the Rat Blood-Brain Barrier: Primary Role of Albumin-Bound Hormone*

31 March 2020

1 reference

Efficacy of multiple-dose halofantrine in treatment of chloroquine-resistant falciparum malaria in children in Kenya

31 March 2020

1 reference

Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid

31 March 2020

1 reference

The stereoselective distribution of halofantrine enantiomers within human, dog, and rat plasma lipoproteins

31 March 2020

1 reference

Antifungal Agents Useful in Therapy of Systemic Fungal Infections

31 March 2020

1 reference

Epidemiology of Candida species infections in critically ill non-immunosuppressed patients

31 March 2020

1 reference

Amphotericin B lipid complex or amphotericin B multiple-dose administration to rabbits with elevated plasma cholesterol levels: pharmacokinetics in plasma and blood, plasma lipoprotein levels, distribution in tissues, and renal toxicities

31 March 2020

1 reference

A kinetic study of the oxidation effects of amphotericin B on human low-density lipoproteins

31 March 2020

1 reference

Preferential distribution of amphotericin B lipid complex into human HDL3 is a consequence of high density lipoprotein coat lipid content

31 March 2020

1 reference

Heat-induced superaggregation of amphotericin B modifies its interaction with serum proteins and lipoproteins and stimulation of TNF-alpha

31 March 2020

1 reference

Effect of dietary oil intake on hepatic cytochrome P450 activity in the rat.

31 March 2020

1 reference

The poloxamer 407-induced hyperlipidemic atherogenic animal model

31 March 2020

1 reference

Acute P-407 administration to mice causes hypercholesterolemia by inducing cholesterolgenesis and down-regulating low-density lipoprotein receptor expression.

31 March 2020

1 reference

Potential downregulation of HMG-CoA reductase after prolonged administration of P-407 in C57BL/6 mice

31 March 2020

1 reference

Hereditary obesity in the rat associated with hyperlipemia

31 March 2020

1 reference

The Zucker rat model of obesity, insulin resistance, hyperlipidemia, and renal injury

31 March 2020

1 reference

Adaptive responses of enzymes of carbohydrate and lipid metabolism to dietary alteration in genetically obese Zucker rats (fa/fa)

31 March 2020

1 reference

Mouse models for atherosclerosis and pharmaceutical modifiers.

31 March 2020

1 reference

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

31 March 2020

1 reference

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

31 March 2020

1 reference

The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins

31 March 2020

1 reference

Cholesteryl ester exchange protein in human plasma isolation and characterization

31 March 2020

1 reference

Isolation and characterization of a human serum cholesteryl ester transfer protein

31 March 2020

1 reference

Molecular mechanism of the blockade of plasma cholesteryl ester transfer protein by its physiological inhibitor apolipoprotein CI

31 March 2020

1 reference

HDL as a target in the treatment of atherosclerotic cardiovascular disease

31 March 2020

1 reference

Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport

31 March 2020

1 reference

Effect of torcetrapib on the progression of coronary atherosclerosis

31 March 2020

1 reference

The low-density lipoprotein receptor gene family: a cellular Swiss army knife?

31 March 2020

1 reference

Expression of LRP1 by human osteoblasts: a mechanism for the delivery of lipoproteins and vitamin K1 to bone

31 March 2020

1 reference

Apolipoprotein E receptors: linking brain development and Alzheimer's disease

31 March 2020

1 reference

Lipoprotein receptors: new roles for ancient proteins.

31 March 2020

1 reference

LRP: a multifunctional scavenger and signaling receptor

31 March 2020

1 reference

Lipoprotein receptors and the genetic control of cholesterol metabolism in cultured human cells

31 March 2020

1 reference

Regulation of the activity of the low density lipoprotein receptor in human fibroblasts

31 March 2020

1 reference

Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts

31 March 2020

1 reference

Dyslipidemia in HIV patients.

31 March 2020

1 reference

Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis

31 March 2020

1 reference

The metabolic basis of atherogenic dyslipidemia

31 March 2020

1 reference

Associations between bipolar disorder and metabolic syndrome: A review.

31 March 2020

1 reference

Rapid cycling bipolar disorder: historical overview and focus on emerging treatments

31 March 2020

1 reference

Plasma protein and lipoprotein distribution of clozapine

31 March 2020

1 reference

Competitive displacement of clozapine from plasma proteins in normolipidemic and hyperlipidemic plasma samples: clinical implications

31 March 2020

1 reference

The influence of hyperlipoproteinemia on in vitro distribution of amiodarone and desethylamiodarone in human and rat plasma

31 March 2020

1 reference

A 4-fold risk of metabolic syndrome in patients with schizophrenia: the Northern Finland 1966 Birth Cohort study

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Plasma distribution of cyclosporine within lipoproteins and "in vitro" transfer between very-low-density lipoproteins, low-density lipoproteins, and high-density lipoproteins

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Physical characteristics and lipoprotein distribution of liposomal nystatin in human plasma

1 reference